Humbert De Smedt

Bcl-2 and IP3 compete for the ligand-binding domain of IP3Rs modulating Ca2+ signaling output

Constitutive IP3 signaling underlies the sensitivity of B-cell cancers to the Bcl-2/IP3 receptor disruptor BIRD-2

Polycystin-2-dependent control of cardiomyocyte autophagy

Altered mTOR signalling in nephropathic cystinosis

The trans-membrane domain of Bcl-2α, but not its hydrophobic cleft, is a critical determinant for efficient IP3 receptor inhibition

The BH4 Domain of Anti-apoptotic Bcl-XL, but Not That of the Related Bcl-2, Limits the Voltage-dependent Anion Channel 1 (VDAC1)-mediated Transfer of Pro-apoptotic Ca2+ Signals to Mitochondria

Autophagy in renal diseases

BAX inhibitor-1 is a Ca2+ channel critically important for immune cell function and survival

A dual role for the anti-apoptotic Bcl-2 protein in cancer: Mitochondria versus endoplasmic reticulum

Inositol 1,4,5-trisphosphate receptor-isoform diversity in cell death and survival

Bcl-2 binds to and inhibits ryanodine receptors

mTOR-Controlled Autophagy Requires Intracellular Ca2+ Signaling

Regulation of inositol 1,4,5-trisphosphate receptors during endoplasmic reticulum stress

Bax Inhibitor-1-mediated Ca2+ leak is decreased by cytosolic acidosis

Inositol 1,4,5-Trisphosphate and Its Receptors

Polycystin-1 and polycystin-2 are both required to amplify inositol-trisphosphate-induced Ca2+ release

Profiling of the Bcl-2/Bcl-XL-binding sites on type 1 IP3 receptor