Area of research
Genetics · Pulmonary and Respiratory Medicine
Research interest
Research interests include Hemoglobinopathies and Related Disorders, Pulmonary Hypertension Research and Treatments, Iron Metabolism and Disorders, and Myeloproliferative Neoplasms: Diagnosis and Treatment.
Nicotinamide phosphoribosyltransferase activates the mitochondrial unfolded protein response to promote pulmonary arterial endothelial cell proliferation
Skeletal Muscle SIRT3 Deficiency Contributes to Pulmonary Vascular Remodeling in Pulmonary Hypertension Due to Heart Failure With Preserved Ejection Fraction
Endothelial knockdown of the tumor suppressor, <i>WWOX</i>, increases inflammation in ventilator-induced lung injury.
Predictors of Methamphetamine Use in the Midwest/Western United States: Xpose
Sphingosine Kinase 1 Deficiency in Smooth Muscle Cells Protects against Hypoxia-Mediated Pulmonary Hypertension via YAP1 Signaling
Cortactin loss protects against hemin-induced acute lung injury in sickle cell disease.
Sphingosine Kinase 1 Regulates the Pulmonary Vascular Immune Response.
IL-18 mediates sickle cell cardiomyopathy and ventricular arrhythmias
Cigarette Smoke and Nicotine-Containing Electronic-Cigarette Vapor Downregulate Lung WWOX Expression, Which is Associated with Increased Severity of Murine Acute Respiratory Distress Syndrome
The <scp><i>CYB5R3</i><sup>c</sup></scp><sup>.<scp>350C</scp>>G</sup> and <scp><i>G6PD</i></scp> A alleles modify severity of anemia in malaria and sickle cell disease
Injury-Induced Shedding of Extracellular Vesicles Depletes Endothelial Cells of Cav-1 (Caveolin-1) and Enables TGF-β (Transforming Growth Factor-β)–Dependent Pulmonary Arterial Hypertension
Injury-Induced Shedding of Extracellular Vesicles Depletes Endothelial Cells of Cav-1 (Caveolin-1) and Enables TGF-β (Transforming Growth Factor-β)-Dependent Pulmonary Arterial Hypertension.
Plexiform Arteriopathy in Rodent Models of Pulmonary Arterial Hypertension.
MicroRNA410 Inhibits Pulmonary Vascular Remodeling via Regulation of Nicotinamide Phosphoribosyltransferase.
Validation of a composite vascular high-risk profile for adult patients with sickle cell disease.
Therapeutic Targeting of Vascular Remodeling and Right Heart Failure in Pulmonary Arterial Hypertension with a HIF-2α Inhibitor
Classification and pathophysiology of pulmonary hypertension
Interaction Between Pannexin 1 and Caveolin-1 in Smooth Muscle Can Regulate Blood Pressure
HMOX1 and acute kidney injury in sickle cell anemia
Vascular complications of sickle cell disease
Risk factors for vitamin D deficiency in sickle cell disease
Hemolysis and hemolysis‐related complications in females vs. males with sickle cell disease
Progressive glomerular and tubular damage in sickle cell trait and sickle cell anemia mouse models
A locus on chromosome 5 shows African ancestry–limited association with alloimmunization in sickle cell disease
Death of the Endothelium in Sepsis: Understanding the Crime Scene
Endothelial nitric oxide synthase genotype is associated with pulmonary hypertension severity in left heart failure patients
A Phase II Clinical Trial of Low-Dose Inhaled Carbon Monoxide in Idiopathic Pulmonary Fibrosis
Nicotinamide Phosphoribosyltransferase Promotes Pulmonary Vascular Remodeling and Is a Therapeutic Target in Pulmonary Arterial Hypertension
Inflammation-induced caveolin-1 and BMPRII depletion promotes endothelial dysfunction and TGF-β-driven pulmonary vascular remodeling
Hemin Causes Lung Microvascular Endothelial Barrier Dysfunction by Necroptotic Cell Death