Area of research
Genetics · Physiology
Research interest
Research interests include Genetic Associations and Epidemiology, Obstructive Sleep Apnea Research, Sleep and related disorders, and Metabolomics and Mass Spectrometry Studies.
Polygenic prediction of body mass index and obesity through the life course and across ancestries
Genome-wide association analysis of composite sleep health scores in 413,904 individuals
A statistical framework for multi-trait rare variant analysis in large-scale whole-genome sequencing studies
Big data approaches for novel mechanistic insights on sleep and circadian rhythms: a workshop summary
Whole genome sequence analysis of low-density lipoprotein cholesterol across 246 K individuals
A Large-Scale Genome-wide Association Study of Blood Pressure Accounting for Gene-Depressive Symptomatology Interactions in 564,680 Individuals from Diverse Populations
Large-Scale Gene-Smoking Interactions and Fine Mapping Study Identifies Multiple Novel Blood Pressure Loci in over 1 Million Individuals
Genetic drivers of heterogeneity in type 2 diabetes pathophysiology
Validation of human telomere length multi-ancestry meta-analysis association signals identifies POP5 and KBTBD6 as human telomere length regulation genes
Clonal haematopoiesis and risk of chronic liver disease
Aberrant activation of TCL1A promotes stem cell expansion in clonal haematopoiesis
Epigenome-wide DNA methylation association study of circulating IgE levels identifies novel targets for asthma
Rare variants in long non-coding RNAs are associated with blood lipid levels in the TOPMed whole-genome sequencing study
The genetic determinants of recurrent somatic mutations in 43,693 blood genomes
Author Correction: Clonal haematopoiesis and risk of chronic liver disease
A saturated map of common genetic variants associated with human height
Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation
Genetic diversity fuels gene discovery for tobacco and alcohol use
A framework for detecting noncoding rare-variant associations of large-scale whole-genome sequencing studies
Genetic determinants of telomere length from 109,122 ancestrally diverse whole-genome sequences in TOPMed
Whole genome sequence analysis of blood lipid levels in >66,000 individuals
Whole Genome Association Study of the Plasma Metabolome Identifies Metabolites Linked to Cardiometabolic Disease in Black Individuals
Powerful, scalable and resource-efficient meta-analysis of rare variant associations in large whole genome sequencing studies
Genetic determinants of cardiometabolic and pulmonary phenotypes and obstructive sleep apnoea in HCHS/SOL
Rare genetic variants explain missing heritability in smoking
Polygenic transcriptome risk scores for COPD and lung function improve cross-ethnic portability of prediction in the NHLBI TOPMed program
A Saturated Map of Common Genetic Variants Associated with Human Height from 5.4 Million Individuals of Diverse Ancestries
Whole genome sequence association analysis of fasting glucose and fasting insulin levels in diverse cohorts from the NHLBI TOPMed program
Rare coding variants in RCN3 are associated with blood pressure
Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program