Area of research
Immunology · Molecular Biology
Research interest
Research interests include T-cell and B-cell Immunology, Immune Cell Function and Interaction, Immunotherapy and Immune Responses, and Sphingolipid Metabolism and Signaling.
Lpar5 regulates the CD8 T-cell response to persistent virus infection by altering exhaustion programming, survival, and NK receptor expression.
Maf expression in B cells restricts reactive plasmablast and germinal center B cell expansion.
Lysophosphatidic acid modulates CD8 T cell immunosurveillance and metabolism to impair anti-tumor immunity.
Lipid mediators in the regulation of innate and adaptive immunity
Lipid mediators in the regulation of innate and adaptive immunity.
Regulation of CD8 T-cell signaling, metabolism, and cytotoxic activity by extracellular lysophosphatidic acid.
SARS-CoV-2 infection relaxes peripheral B cell tolerance.
Active PI3K abrogates central tolerance in high-avidity autoreactive B cells.
Murine gammaherpesvirus 68 infection protects lupus-prone mice from the development of autoimmunity