Area of research
Molecular Biology · Cell Biology
Research interest
Research interests include Protein Degradation and Inhibitors, Microtubule and mitosis dynamics, Ubiquitin and proteasome pathways, and Nuclear Structure and Function.
Defining the Antitumor Mechanism of Action of a Clinical-stage Compound as a Selective Degrader of the Nuclear Pore Complex
Abstract LB195: Activity based protein profiling on kinase PROTACs leads to the discovery of selective APT1/2 degrader
Convergence of coronary artery disease genes onto endothelial cell programs
Lactate regulates cell cycle by remodelling the anaphase promoting complex
Chemical Specification of E3 Ubiquitin Ligase Engagement by Cysteine-Reactive Chemistry
Recognition of centromere‐specific histone Cse4 by the inner kinetochore Okp1‐Ame1 complex
Recognition of Divergent Viral Substrates by the SARS-CoV-2 Main Protease
Ctf3/CENP-I provides a docking site for the desumoylase Ulp2 at the kinetochore
The Structural Basis for Kinetochore Stabilization by Cnn1/CENP-T
The structure of the Ctf19c/CCAN from budding yeast
The structure of the yeast Ctf3 complex
The Kinetochore Receptor for the Cohesin Loading Complex
Kinetochore Function from the Bottom Up
An Iml3-Chl4 Heterodimer Links the Core Centromere to Factors Required for Accurate Chromosome Segregation