Area of research
Physiology · Molecular Biology
Research interest
Research interests include Adipose Tissue and Metabolism, Mitochondrial Function and Pathology, Muscle metabolism and nutrition, and Cancer, Hypoxia, and Metabolism.
Mitochondrial complex III-derived ROS amplify immunometabolic changes in astrocytes and promote dementia pathology
Covariation MS uncovers a protein that controls cysteine catabolism
The human zinc-binding cysteine proteome
Lactate regulates cell cycle by remodelling the anaphase promoting complex
Exercise preserves physical fitness during aging through AMPK and mitochondrial dynamics
Chemical Specification of E3 Ubiquitin Ligase Engagement by Cysteine-Reactive Chemistry
Depletion of creatine phosphagen energetics with a covalent creatine kinase inhibitor
Mitochondrial uncouplers induce proton leak by activating AAC and UCP1
Architecture of the outbred brown fat proteome defines regulators of metabolic physiology
Glycogen metabolism links glucose homeostasis to thermogenesis in adipocytes
Glucose metabolism and pyruvate carboxylase enhance glutathione synthesis and restrict oxidative stress in pancreatic islets
A Quantitative Tissue-Specific Landscape of Protein Redox Regulation during Aging
pH-Gated Succinate Secretion Regulates Muscle Remodeling in Response to Exercise
Metabolic adaptation and maladaptation in adipose tissue
New Advances in Adaptive Thermogenesis: UCP1 and Beyond
Coupling Krebs cycle metabolites to signalling in immunity and cancer
Genetic Depletion of Adipocyte Creatine Metabolism Inhibits Diet-Induced Thermogenesis and Drives Obesity
A Creatine-Driven Substrate Cycle Enhances Energy Expenditure and Thermogenesis in Beige Fat