Area of research
Immunology · Molecular Biology
Research interest
Research interests include Inflammasome and immune disorders, interferon and immune responses, Immune Cell Function and Interaction, and Immunotherapy and Immune Responses.
STING signals to NF-κB from late endolysosomal compartments using IRF3 as an adaptor.
Universal STING mimic boosts antitumour immunity via preferential activation of tumour control signalling pathways
Initiator cell death event induced by SARS-CoV-2 in the human airway epithelium.
IL-11 induces NLRP3 inflammasome activation in monocytes and inflammatory cell migration to the central nervous system
An epithelial-immune circuit amplifies inflammasome and IL-6 responses to SARS-CoV-2.
Optineurin regulates NRF2-mediated antioxidant response in a mouse model of Paget's disease of bone.
Convergence of Targeted and Immune Therapies for the Treatment of Oncogene-Driven Cancers.
Zinc cyclic di-AMP nanoparticles target and suppress tumours via endothelial STING activation and tumour-associated macrophage reinvigoration
Infection and inflammation: New perspectives on Alzheimer's disease
AIM2 in regulatory T cells restrains autoimmune diseases
Multi-omics analyses reveal that HIV-1 alters CD4+ T cell immunometabolism to fuel virus replication
Move over NAIP, DDX17 diversifies the NLRC4 inflammasome.
Multi-omics analyses of radiation survivors identify radioprotective microbes and metabolites
Multi-omics analyses of radiation survivors identify radioprotective microbes and metabolites.
The NLRP3 inflammasome: molecular activation and regulation to therapeutics
Platelet-activating factor (PAF) mediates NLRP3-NEK7 inflammasome induction independently of PAFR
A noncanonical function of cGAMP in inflammasome priming and activation
How Mouse Macrophages Sense What Is Going On
Inflammasomes: mechanism of action, role in disease, and therapeutics
The linear ubiquitin assembly complex (LUBAC) is essential for NLRP3 inflammasome activation
Cyclic‐di‐GMP and cyclic‐di‐AMP activate the NLRP3 inflammasome
Novel role of PKR in inflammasome activation and HMGB1 release
Autophagy Links Inflammasomes to Atherosclerotic Progression
NLRP12 Suppresses Colon Inflammation and Tumorigenesis through the Negative Regulation of Noncanonical NF-κB Signaling
Plexin-B2 and Plexin-D1 in Dendritic Cells: Expression and IL-12/IL-23p40 Production