Area of research
Molecular Biology
Research interest
Research interests include RNA Research and Splicing, Genomics and Chromatin Dynamics, RNA modifications and cancer, and RNA and protein synthesis mechanisms.
An atlas of substrate specificities for the human serine/threonine kinome
The Mediator complex as a master regulator of transcription by RNA polymerase II
Partitioning of cancer therapeutics in nuclear condensates
Pol II phosphorylation regulates a switch between transcriptional and splicing condensates
Mediator Condensates Localize Signaling Factors to Key Cell Identity Genes
Transcription Factors Activate Genes through the Phase-Separation Capacity of Their Activation Domains
Backtracked and paused transcription initiation intermediate of <i>Escherichia coli</i> RNA polymerase
Mediator kinase inhibition further activates super-enhancer-associated genes in AML
Architecture of the Human and Yeast General Transcription and DNA Repair Factor TFIIH
TRIM28 regulates RNA polymerase II promoter-proximal pausing and pause release
Structural visualization of key steps in human transcription initiation