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Gabriel C. Lander

University of California, Berkeley · US
Area of research
Structural Biology · Molecular Biology
Research interest
Research interests include Biology, Cell biology, Proteasome, Protein subunit, Biophysics, and Ubiquitin.
h-index
citations
3,652
works
25
NIH funding
primary concept
email

Recent publications

<i>Magellon</i> – an extensible platform for cryo-EM data visualization, management and processing
IUCrJ 2025cited by 2position: middledoi
CryoSift - An accessible and automated CNN-driven tool for cryo-EM 2D class selection
bioRxiv (Cold Spring Harbor Laboratory) 2025cited by 2position: middledoi
<i>CryoSift</i> : an accessible and automated CNN-driven tool for cryo-EM 2D class selection
Acta Crystallographica Section F Structural Biology Communications 2025cited by 1position: middledoi
Community recommendations on cryoEM data archiving and validation
IUCrJ 2024cited by 33position: middledoi
Bis-sulfonamido-2-phenylbenzoxazoles Validate the GroES/EL Chaperone System as a Viable Antibiotic Target
Journal of the American Chemical Society 2024cited by 9position: middledoi
DELE1 oligomerization promotes integrated stress response activation
Nature Structural & Molecular Biology 2023cited by 46position: lastdoi
The N1 domain of the peroxisomal AAA-ATPase Pex6 is required for Pex15 binding and proper assembly with Pex1
Journal of Biological Chemistry 2023cited by 6position: middledoi
Structure of the hepatitis C virus E1E2 glycoprotein complex
Science 2022cited by 85position: middledoi
Coupling of distant ATPase domains in the circadian clock protein KaiC
Nature Structural & Molecular Biology 2022cited by 23position: middledoi
Sub-2 Angstrom resolution structure determination using single-particle cryo-EM at 200 keV
Journal of Structural Biology X 2020cited by 76position: middledoi
Dynamics at the serine loop underlie differential affinity of cryptochromes for CLOCK:BMAL1 to control circadian timing
eLife 2020cited by 74position: middledoi
High-resolution structure determination of sub-100 kDa complexes using conventional cryo-EM
Nature Communications 2019cited by 239position: lastdoi
Current outcomes when optimizing ‘standard’ sample preparation for single‐particle cryo‐EM
Journal of Microscopy 2019cited by 70position: middledoi
Specific lid-base contacts in the 26s proteasome control the conformational switching required for substrate degradation
eLife 2019cited by 41position: middledoi
Substrate-engaged 26 <i>S</i> proteasome structures reveal mechanisms for ATP-hydrolysis–driven translocation
Science 2018cited by 328position: middledoi
Cryo-electron tomography reveals that dynactin recruits a team of dyneins for processive motility
Nature Structural & Molecular Biology 2018cited by 148position: lastdoi
A Multi-model Approach to Assessing Local and Global Cryo-EM Map Quality
Structure 2018cited by 67position: lastdoi
The peroxisomal AAA-ATPase Pex1/Pex6 unfolds substrates by processive threading
Nature Communications 2018cited by 65position: middledoi
Structure Reveals Mechanisms of Viral Suppressors that Intercept a CRISPR RNA-Guided Surveillance Complex
Cell 2017cited by 230position: middledoi
Cas1 and the Csy complex are opposing regulators of Cas2/3 nuclease activity
Proceedings of the National Academy of Sciences 2017cited by 96position: middledoi
Atomic structure of the 26S proteasome lid reveals the mechanism of deubiquitinase inhibition
eLife 2016cited by 105position: lastdoi
Structural organization of the dynein–dynactin complex bound to microtubules
Nature Structural & Molecular Biology 2015cited by 202position: lastdoi
Protein domain mapping by internal labeling and single particle electron microscopy
Journal of Structural Biology 2015cited by 15position: middledoi
High-Resolution Microtubule Structures Reveal the Structural Transitions in αβ-Tubulin upon GTP Hydrolysis
Cell 2014cited by 723position: middledoi
Characterization of virus-like particles in GARDASIL® by cryo transmission electron microscopy
Human Vaccines & Immunotherapeutics 2013cited by 70position: middledoi
The proteasome under the microscope: the regulatory particle in focus
Current Opinion in Structural Biology 2013cited by 36position: firstdoi
Complete subunit architecture of the proteasome regulatory particle
Nature 2012cited by 619position: firstdoi
Molecular architecture of human polycomb repressive complex 2
eLife 2012cited by 239position: middledoi
Go hybrid: EM, crystallography, and beyond
Current Opinion in Structural Biology 2012cited by 40position: firstdoi

Grants

No grants ingested yet.

Frequent collaborators

Eva Nogales · Howard Hughes Medical Institute7 papers (2012–2019)Andreas Martin · QB37 papers (2012–2023)Saikat Chowdhury · Pennsylvania State University6 papers (2015–2023)Mark A. Herzik · University of California San Diego4 papers (2016–2020)Michael A. Cianfrocco · MetLife (United States)3 papers (2025–2025)Scott M. Stagg · Florida State University3 papers (2025–2025)Puneeth Damodar · Florida State University3 papers (2025–2025)Jan-Hannes Schäfer · Scripps Institution of Oceanography3 papers (2025–2025) · 2 papers (2017–2017)Bridget Carragher · New York Structural Biology Center2 papers (2013–2019)Andres H. de la Peña · Johns Hopkins Medicine2 papers (2018–2019)Ellen A. Goodall · University of California, Berkeley2 papers (2018–2019)Joshua Carter · Indiana University Bloomington2 papers (2017–2017)Colby R. Sandate · Scripps Institution of Oceanography2 papers (2020–2022)Claudio Ciferri · University of California, Berkeley2 papers (2012–2015)Mary E. Matyskiela · Bristol-Myers Squibb (United States)2 papers (2012–2019) · 2 papers (2017–2017)Mengyu Wu · Lawrence Berkeley National Laboratory2 papers (2019–2020)Dominic T. Castanzo · University of California System2 papers (2018–2023)Nebojša Bogdanović · Case Western Reserve University2 papers (2025–2025)