Area of research
Immunology · Oncology
Research interest
Research interests include CAR-T cell therapy research, Immune Cell Function and Interaction, T-cell and B-cell Immunology, and Immunotherapy and Immune Responses.
Cancer immunology data engine reveals secreted AOAH as a potential immunotherapy
TCR ligand potency differentially impacts PD-1 inhibitory effects on diverse signaling pathways
Systematic investigation of cytokine signaling activity at the tissue and single-cell levels
A local regulatory T cell feedback circuit maintains immune homeostasis by pruning self-activated T cells
β-Coronaviruses Use Lysosomes for Egress Instead of the Biosynthetic Secretory Pathway
Defective glycosylation and multisystem abnormalities characterize the primary immunodeficiency XMEN disease
IL-2 production by self-reactive CD4 thymocytes scales regulatory T cell generation in the thymus
A Tunable Diffusion-Consumption Mechanism of Cytokine Propagation Enables Plasticity in Cell-to-Cell Communication in the Immune System
Catch and Release of Cytokines Mediated by Tumor Phosphatidylserine Converts Transient Exposure into Long-Lived Inflammation
EGFR and PDGFRA co-expression and heterodimerization in glioblastoma tumor sphere lines
JAK2 inhibition sensitizes resistant EGFR-mutant lung adenocarcinoma to tyrosine kinase inhibitors
Clonal Abundance of Tumor-Specific CD4 + T Cells Potentiates Efficacy and Alters Susceptibility to Exhaustion
Phosphatidylserine Vesicles Enable Efficient En Bloc Transmission of Enteroviruses
T Cells Integrate Local and Global Cues to Discriminate between Structurally Similar Antigens
Computational Algorithm-Driven Evaluation of Monocytic Myeloid-Derived Suppressor Cell Frequency for Prediction of Clinical Outcomes
The IL-6/JAK/Stat3 Feed-Forward Loop Drives Tumorigenesis and Metastasis
Competition for IL-2 between Regulatory and Effector T Cells to Chisel Immune Responses
Distinct influences of peptide-MHC quality and quantity on in vivo T-cell responses