Bibi Kassim

Heterogeneous epigenetic variation converges on splicing dysregulation in opioid addiction

Single chromatin fiber profiling and nucleosome position mapping in the human brain

Chromatin domain alterations linked to 3D genome organization in a large cohort of schizophrenia and bipolar disorder brains

Population-level variation in enhancer expression identifies disease mechanisms in the human brain

Targeting histone demethylase LSD1 for treatment of deficits in autism mouse models

HIV integration in the human brain is linked to microglial activation and 3D genome remodeling

Convergence of case-specific epigenetic alterations identify a confluence of genetic vulnerabilities tied to opioid overdose

HIV integration in the human brain is linked to microglial activation and 3D genome remodeling

Neuronal and glial 3D chromatin architecture informs the cellular etiology of brain disorders

Common Genetic Variation in Humans Impacts In Vitro Susceptibility to SARS-CoV-2 Infection

Convergence of case-specific epigenetic alterations identify a confluence of genetic vulnerabilities tied to opioid dependence

Acetylated Chromatin Domains Link Chromosomal Organization to Cell- and Circuit-level Dysfunction in Schizophrenia and Bipolar Disorder

Large eQTL meta-analysis reveals differing patterns between cerebral cortical and cerebellar brain regions

Functional annotation of rare structural variation in the human brain

A chromosomal connectome for psychiatric and metabolic risk variants in adult dopaminergic neurons

Neuronal and glial 3D chromatin architecture illustrates cellular etiology of brain disorders

Common genetic variation in humans impacts <i>in vitro</i> susceptibility to SARS-CoV-2 infection

Transcriptome-wide isoform-level dysregulation in ASD, schizophrenia, and bipolar disorder

Comprehensive functional genomic resource and integrative model for the human brain

Integrative functional genomic analysis of human brain development and neuropsychiatric risks

Neuron-specific signatures in the chromosomal connectome associated with schizophrenia risk

Cell-specific histone modification maps in the human frontal lobe link schizophrenia risk to the neuronal epigenome

The methyltransferase SETDB1 regulates a large neuron-specific topological chromatin domain

The epigenomics of schizophrenia, in the mouse

Practical Guidelines for High-Resolution Epigenomic Profiling of Nucleosomal Histones in Postmortem Human Brain Tissue

Neuronal Deletion of Kmt2a/Mll1 Histone Methyltransferase in Ventral Striatum is Associated with Defective Spike-Timing-Dependent Striatal Synaptic Plasticity, Altered Response to Dopaminergic Drugs, and Increased Anxiety