Area of research
Molecular Biology · Neurology
Research interest
Research interests include Neuroinflammation and Neurodegeneration Mechanisms, Epigenetics and DNA Methylation, Genetics and Neurodevelopmental Disorders, and Tryptophan and brain disorders.
tRNA epitranscriptomic alterations associated with opioid-induced reward-seeking and long-term opioid withdrawal in male mice
Single chromatin fiber profiling and nucleosome position mapping in the human brain
Neuron-Specific Glycine Metabolism Links Transfer RNA Epitranscriptomic Regulation to Complex Behaviors
HIV-1 infection of genetically engineered iPSC-derived central nervous system-engrafted microglia in a humanized mouse model
R-loop landscapes in the developing human brain are linked to neural differentiation and cell type-specific transcription
HIV-1 infection of genetically engineered iPSC-derived central nervous system-engrafted microglia in a humanized mouse model
Targeting histone demethylase LSD1 for treatment of deficits in autism mouse models
HIV integration in the human brain is linked to microglial activation and 3D genome remodeling
Cylindromatosis drives synapse pruning and weakening by promoting macroautophagy through Akt-mTOR signaling
HIV integration in the human brain is linked to microglial activation and 3D genome remodeling
Single-nucleus transcriptome analysis of human brain immune response in patients with severe COVID-19
Neuronal Nsun2 deficiency produces tRNA epitranscriptomic alterations and proteomic shifts impacting synaptic signaling and behavior
Author Correction: Neuronal Nsun2 deficiency produces tRNA epitranscriptomic alterations and proteomic shifts impacting synaptic signaling and behavior
The landscape of human brain immune response in patients with severe COVID-19
Cylindromatosis Drives Synapse Pruning and Weakening by Promoting Macroautophagy through Akt-mTOR Signaling
A chromosomal connectome for psychiatric and metabolic risk variants in adult dopaminergic neurons
Neuron-specific signatures in the chromosomal connectome associated with schizophrenia risk
The methyltransferase SETDB1 regulates a large neuron-specific topological chromatin domain
MEF2C transcription factor is associated with the genetic and epigenetic risk architecture of schizophrenia and improves cognition in mice
Phf8 loss confers resistance to depression-like and anxiety-like behaviors in mice
The epigenomics of schizophrenia, in the mouse
Neuronal Deletion of Kmt2a/Mll1 Histone Methyltransferase in Ventral Striatum is Associated with Defective Spike-Timing-Dependent Striatal Synaptic Plasticity, Altered Response to Dopaminergic Drugs, and Increased Anxiety
NeuN+ neuronal nuclei in non-human primate prefrontal cortex and subcortical white matter after clozapine exposure
Longitudinal assessment of neuronal 3D genomes in mouse prefrontal cortex
Neuronal Kmt2a/Mll1 Histone Methyltransferase Is Essential for Prefrontal Synaptic Plasticity and Working Memory