Area of research
Hematology · Molecular Biology
Research interest
Research interests include Acute Myeloid Leukemia Research, Protein Degradation and Inhibitors, Epigenetics and DNA Methylation, and Genetics and Neurodevelopmental Disorders.
Continuous cell-type diversification in mouse visual cortex development
KDM6 demethylases integrate DNA repair gene regulation and loss of KDM6A sensitizes human acute myeloid leukemia to PARP and BCL2 inhibition
A cellular hierarchy framework for understanding heterogeneity and predicting drug response in acute myeloid leukemia
Cerebral Microbleeds, Cerebral Amyloid Angiopathy, and Their Relationships to Quantitative Markers of Neurodegeneration
Chromatin profiling of cortical neurons identifies individual epigenetic signatures in schizophrenia
Epigenetic‐genetic chromatin footprinting identifies novel and subject‐specific genes active in prefrontal cortex neurons
MEF2C transcription factor is associated with the genetic and epigenetic risk architecture of schizophrenia and improves cognition in mice
Cocaine-Induced Chromatin Modifications Associate With Increased Expression and Three-Dimensional Looping of Auts2
159. The Largest Number of Cocaine-Induced Changes in Chromatin Modifications Are Associated with Increased Expression and 3D Looping of Auts2
A 17-gene stemness score for rapid determination of risk in acute leukaemia
miR-126 Regulates Distinct Self-Renewal Outcomes in Normal and Malignant Hematopoietic Stem Cells
Disruption of an Evolutionarily Novel Synaptic Expression Pattern in Autism
Neuronal Deletion of Kmt2a/Mll1 Histone Methyltransferase in Ventral Striatum is Associated with Defective Spike-Timing-Dependent Striatal Synaptic Plasticity, Altered Response to Dopaminergic Drugs, and Increased Anxiety
NeuN+ neuronal nuclei in non-human primate prefrontal cortex and subcortical white matter after clozapine exposure
Longitudinal assessment of neuronal 3D genomes in mouse prefrontal cortex
Cocaine‐induced chromatin modifications are associated with increased gene expression and DNA‐DNA interactions of AUTS2
Epigenetic Basis of Mental Illness
Neuronal Kmt2a/Mll1 Histone Methyltransferase Is Essential for Prefrontal Synaptic Plasticity and Working Memory
Interneuron epigenomes during the critical period of cortical plasticity: Implications for schizophrenia
A Role for Noncoding Variation in Schizophrenia
Conserved Higher-Order Chromatin Regulates NMDA Receptor Gene Expression and Cognition
Transcriptional regulation of GAD1 GABA synthesis gene in the prefrontal cortex of subjects with schizophrenia
The Genome in Three Dimensions: A New Frontier in Human Brain Research
Prefrontal Cortical Dysfunction After Overexpression of Histone Deacetylase 1
Human-Specific Histone Methylation Signatures at Transcription Start Sites in Prefrontal Neurons