Area of research
Molecular Biology · Genetics
Research interest
Research interests include Genetic Associations and Epidemiology, Epigenetics and DNA Methylation, Single-cell and spatial transcriptomics, and Bioinformatics and Genomic Networks.
Biological insights into schizophrenia from ancestrally diverse populations
GROMTools: scalable individual-level GReX imputation for mega-biobank-scale cohorts
Long-read RNA sequencing atlas of human microglia isoforms elucidates disease-associated genetic regulation of splicing
Multiomic single-cell profiling identifies critical regulators of postnatal brain
Alzheimer’s disease transcriptional landscape in ex vivo human microglia
Fast, flexible analysis of differences in cellular composition with crumblr
The neuronal chromatin landscape in brains from individuals with schizophrenia is linked to early fetal development
A Transcriptomic Roadmap of Parkinson’s Disease Progression at Single Cell Resolution
A genetically based computational drug repurposing framework for rapid identification of candidate compounds: application to COVID-19
Sex Differences in Brain Cell Type–Specific Chromatin Accessibility in Schizophrenia
Single-cell genomics and regulatory networks for 388 human brains
Single-cell multi-cohort dissection of the schizophrenia transcriptome
Massively parallel characterization of regulatory elements in the developing human cortex
Cross-ancestry atlas of gene, isoform, and splicing regulation in the developing human brain
Genetic regulation of cell type–specific chromatin accessibility shapes brain disease etiology
Single-cell atlas of transcriptomic vulnerability across multiple neurodegenerative and neuropsychiatric diseases
Single-cell genomics and regulatory networks for 388 human brains
A lifespan transcriptomic atlas of the human prefrontal cortex at single-cell resolution
A multi-regional human brain atlas of chromatin accessibility and gene expression facilitates promoter-isoform resolution genetic fine-mapping
Biological Insights from Schizophrenia-associated Loci in Ancestral Populations
Phenotype Scoring of Population Scale Single-Cell Data Dissects Alzheimer’s Disease Complexity
Neuropsychiatric polygenic scores are weak predictors of professional categories
Genome-wide analyses of ADHD identify 27 risk loci, refine the genetic architecture and implicate several cognitive domains
Efficient differential expression analysis of large-scale single cell transcriptomics data using dreamlet
Activity-Dependent Transcriptional Program in NGN2+ Neurons Enriched for Genetic Risk for Brain-Related Disorders
Plasticity of Human Microglia and Brain Perivascular Macrophages in Aging and Alzheimer’s Disease
Author Correction: Genome-wide analyses of ADHD identify 27 risk loci, refine the genetic architecture and implicate several cognitive domains
Detecting and Adjusting for Hidden Biases due to Phenotype Misclassification in Genome-Wide Association Studies
Convergence of the dysregulated regulome in schizophrenia with polygenic risk and evolutionarily constrained enhancers
Genetic regulation of cell-type specific chromatin accessibility shapes the etiology of brain diseases