Area of research
Molecular Biology · Genetics
Research interest
Research interests include Epigenetics and DNA Methylation, Genomics and Chromatin Dynamics, Genetic Associations and Epidemiology, and RNA Research and Splicing.
Long-read RNA sequencing atlas of human microglia isoforms elucidates disease-associated genetic regulation of splicing
Alzheimer’s disease transcriptional landscape in ex vivo human microglia
The neuronal chromatin landscape in brains from individuals with schizophrenia is linked to early fetal development
Single-cell multi-cohort dissection of the schizophrenia transcriptome
Massively parallel characterization of regulatory elements in the developing human cortex
Genetic regulation of cell type–specific chromatin accessibility shapes brain disease etiology
Transcriptomic sex differences in postmortem brain samples from patients with psychiatric disorders
Dynamic alterations in gene co-expression networks and gene-transcript associations characterize co-morbidities in cocaine use disorder
Schizophrenia risk conferred by rare protein-truncating variants is conserved across diverse human populations
Lineage specific 3D genome structure in the adult human brain and neurodevelopmental changes in the chromatin interactome
Plasticity of Human Microglia and Brain Perivascular Macrophages in Aging and Alzheimer’s Disease
Genetic regulation of cell-type specific chromatin accessibility shapes the etiology of brain diseases
The neuronal chromatin landscape in adult schizophrenia brains is linked to early fetal development
Long-read RNA-seq atlas of novel microglia isoforms elucidates disease-associated genetic regulation of splicing
Genetics of the human microglia regulome refines Alzheimer’s disease risk loci
The three-dimensional landscape of cortical chromatin accessibility in Alzheimer’s disease
Population-level variation in enhancer expression identifies disease mechanisms in the human brain
Genetics of the human microglia regulome refines Alzheimer’s disease risk loci
The three-dimensional landscape of chromatin accessibility in Alzheimer’s disease
From compartments to gene loops: Functions of the 3D genome in the human brain
Hypothalamic Fkbp51 is induced by fasting, and elevated hypothalamic expression promotes obese phenotypes