Area of research
Molecular Biology · Cellular and Molecular Neuroscience
Research interest
Research interests include Neurotransmitter Receptor Influence on Behavior, Genetic Associations and Epidemiology, CRISPR and Genetic Engineering, and Autism Spectrum Disorder Research.
Functional implications of polygenic risk for schizophrenia in human neurons
Estradiol modulates neuronal network hyperexcitability in select NDD risk genes
Transcriptomic and phenotypic convergence of neurodevelopmental disorder risk genes in vitro and in vivo
Dynamic neuro-immune regulation of psychiatric risk loci in human neurons
Dynamic convergence of neurodevelopmental disorder risk genes across neurodevelopment
Lineage specific 3D genome structure in the adult human brain and neurodevelopmental changes in the chromatin interactome
Common genetic variation impacts stress response in the brain
Non-additive effects of schizophrenia risk genes reflect convergent downstream function
R-loop landscapes in the developing human brain are linked to neural differentiation and cell type-specific transcription
The three-dimensional landscape of cortical chromatin accessibility in Alzheimer’s disease
Population-level variation in enhancer expression identifies disease mechanisms in the human brain
Convergent and non-additive impact of schizophrenia risk genes in human neurons
Reduced LYNX1 expression in transcriptome of human iPSC-derived neural progenitors modeling fragile X syndrome
Induction of dopaminergic neurons for neuronal subtype-specific modeling of psychiatric disease risk
Using the dCas9-KRAB system to repress gene expression in hiPSC-derived NGN2 neurons
From compartments to gene loops: Functions of the 3D genome in the human brain
Induction of Dopaminergic Neurons for Neuronal Subtype-Specific Modeling of Psychiatric Disease Risk
Population-level variation of enhancer expression identifies novel disease mechanisms in the human brain
Massively parallel techniques for cataloguing the regulome of the human brain