Area of research
Molecular Biology
Research interest
Research interests include Pluripotent Stem Cells Research, CRISPR and Genetic Engineering, Single-cell and spatial transcriptomics, and Bioinformatics and Genomic Networks.
Functional implications of polygenic risk for schizophrenia in human neurons
Non-additive effects of schizophrenia risk genes reflect convergent downstream function
Chromatin profiling in human neurons reveals aberrant roles for histone acetylation and BET family proteins in schizophrenia
Convergent and non-additive impact of schizophrenia risk genes in human neurons
Analysis framework and experimental design for evaluating synergy-driving gene expression
Using the dCas9-KRAB system to repress gene expression in hiPSC-derived NGN2 neurons
Transformative Network Modeling of Multi-omics Data Reveals Detailed Circuits, Key Regulators, and Potential Therapeutics for Alzheimer’s Disease
Integration of CRISPR-engineering and hiPSC-based models of psychiatric genomics
Synergistic effects of common schizophrenia risk variants
Neuronal impact of patient-specific aberrant NRXN1α splicing
Molecular Networks and Key Regulators of the Dysregulated Neuronal System in Alzheimer’s Disease
Neuron-specific signatures in the chromosomal connectome associated with schizophrenia risk
New considerations for hiPSC-based models of neuropsychiatric disorders
AID stabilizes stem-cell phenotype by removing epigenetic memory of pluripotency genes