Area of research
Molecular Biology · Genetics
Research interest
Research interests include CRISPR and Genetic Engineering, Gene Regulatory Network Analysis, Genomics and Chromatin Dynamics, and Evolution and Genetic Dynamics.
Genome duplication in a long-term multicellularity evolution experiment
Brainwide silencing of prion protein by AAV-mediated delivery of an engineered compact epigenetic editor
Development of compact transcriptional effectors using high-throughput measurements in diverse contexts
Anti-CRISPR Anopheles mosquitoes inhibit gene drive spread under challenging behavioural conditions in large cages
Structural Mapping of Protein Aggregates in Live Cells Modeling Huntington's Disease
Mapping the dynamics of epigenetic adaptation in S. pombe during heterochromatin misregulation
Unlocking the magic in mycelium: Using synthetic biology to optimize filamentous fungi for biomanufacturing and sustainability
A Multiplex MoClo Toolkit for Extensive and Flexible Engineering of <i>Saccharomyces cerevisiae</i>
Cooperative assembly confers regulatory specificity and long-term genetic circuit stability
Transcriptional kinetic synergy: A complex landscape revealed by integrating modeling and synthetic biology
Effects of antibiotic interaction on antimicrobial resistance development in wastewater
The sound of silence: Transgene silencing in mammalian cell engineering
Modular design of synthetic receptors for programmed gene regulation in cell therapies
Multidimensional control of therapeutic human cell function with synthetic gene circuits
In vivo hypermutation and continuous evolution
High-throughput continuous evolution of compact Cas9 variants targeting single-nucleotide-pyrimidine PAMs
High-performance multiplex drug-gated CAR circuits
In vivo hypermutation and continuous evolution
A Toolkit for Precise, Multigene Control in <i>Saccharomyces cerevisiae</i>
Screening microbially produced Δ9-tetrahydrocannabinol using a yeast biosensor workflow
Recent progress of gene circuit designs in immune cell therapies
Enhancing nutritional niche and host defenses by modifying the gut microbiome
A Code of Ethics for Gene Drive Research
Computational Model To Quantify the Growth of Antibiotic-Resistant Bacteria in Wastewater
Protein assembly systems in natural and synthetic biology
Automated Continuous Evolution of Proteins <i>in Vivo</i>
Barcoded microbial system for high-resolution object provenance
Colonization with heterologous bacteria reprograms a <i>Caenorhabditis elegans</i> nutritional phenotype
Functional genomics of the rapidly replicating bacterium Vibrio natriegens by CRISPRi
Complex signal processing in synthetic gene circuits using cooperative regulatory assemblies