Area of research
Physiology · Neurology
Research interest
Research interests include Biology, Neuroscience, Disease, Microglia, Cell biology, and Phenotype.
CLU alleviates Alzheimer’s disease-relevant processes by modulating astrocyte reactivity and microglia-dependent synaptic density
Astrocyte induction of disease-associated microglia is suppressed by acute exposure to fAD neurons in human iPSC triple cultures
Contributions of Genetic Variation in Astrocytes to Cell and Molecular Mechanisms of Risk and Resilience to Late‐Onset Alzheimer's Disease
Cell subtype-specific effects of genetic variation in the Alzheimer’s disease brain
Person‐specific differences in ubiquitin‐proteasome mediated proteostasis in human neurons
INPP5D regulates inflammasome activation in human microglia
Cell-type-specific regulation of APOE and CLU levels in human neurons by the Alzheimer’s disease risk gene SORL1
Predictive network analysis identifies JMJD6 and other potential key drivers in Alzheimer’s disease
RNA-binding protein ELAVL4/HuD ameliorates Alzheimer's disease-related molecular changes in human iPSC-derived neurons
APP and DYRK1A regulate axonal and synaptic vesicle protein networks and mediate Alzheimer’s pathology in trisomy 21 neurons
Stem cell-derived neurons reflect features of protein networks, neuropathology, and cognitive outcome of their aged human donors
Convergence of independent DISC1 mutations on impaired neurite growth via decreased UNC5D expression
Cell-type Dependent Alzheimer's Disease Phenotypes: Probing the Biology of Selective Neuronal Vulnerability