Area of research
Neurology · Physiology
Research interest
Research interests include Biology, Neuroscience, Microglia, Disease, Cell type, and Neurodegeneration.
Cellular communities reveal trajectories of brain ageing and Alzheimer’s disease
A cross-disease resource of living human microglia identifies disease-enriched subsets and tool compounds recapitulating microglial states
Multicellular communities are perturbed in the aging human brain and Alzheimer’s disease
INPP5D regulates inflammasome activation in human microglia
Cell-type-specific regulation of APOE and CLU levels in human neurons by the Alzheimer’s disease risk gene SORL1
Cellular dynamics across aged human brains uncover a multicellular cascade leading to Alzheimer’s disease
Cellular network perturbations point to a new microglia‐astrocyte community accelerating Alzheimer’s disease progression
Single cell RNA sequencing of human microglia uncovers a subset associated with Alzheimer’s disease
Deconvolving the contributions of cell-type heterogeneity on cortical gene expression
A molecular network of the aging human brain provides insights into the pathology and cognitive decline of Alzheimer’s disease