Area of research
Molecular Biology · Neurology
Research interest
Research interests include Single-cell and spatial transcriptomics, Neuroinflammation and Neurodegeneration Mechanisms, Bioinformatics and Genomic Networks, and CRISPR and Genetic Engineering.
Human subcutaneous and visceral adipocyte atlases uncover classical and nonclassical adipocytes and depot-specific patterns
Cell subtype-specific effects of genetic variation in the Alzheimer’s disease brain
Cellular communities reveal trajectories of brain ageing and Alzheimer’s disease
A cross-disease resource of living human microglia identifies disease-enriched subsets and tool compounds recapitulating microglial states
Molecular connectomics reveals a glucagon-like peptide 1-sensitive neural circuit for satiety
Opportunities and challenges of single-cell and spatially resolved genomics methods for neuroscience discovery
Implementation and validation of single-cell genomics experiments in neuroscience
Applying single-cell and single-nucleus genomics to studies of cellular heterogeneity and cell fate transitions in the nervous system
Multicellular communities are perturbed in the aging human brain and Alzheimer’s disease
N-acetylneuraminic acid links immune exhaustion and accelerated memory deficit in diet-induced obese Alzheimer’s disease mouse model
Deep brain stimulation of thalamic nucleus reuniens promotes neuronal and cognitive resilience in an Alzheimer’s disease mouse model
A Single-Nucleus Transcriptome-Wide Association Study Implicates Novel Genes in Depression Pathogenesis
Non-invasive assessment of normal and impaired iron homeostasis in the brain
Claustral neurons projecting to frontal cortex restrict opioid consumption
Cellular dynamics across aged human brains uncover a multicellular cascade leading to Alzheimer’s disease
Stroke genetics informs drug discovery and risk prediction across ancestries
High‐throughput morphometric and transcriptomic profiling uncovers composition of naïve and sensory‐deprived cortical cholinergic VIP/CHAT neurons
Publisher Correction: Stroke genetics informs drug discovery and risk prediction across ancestries
Stroke genetics informs drug discovery and risk prediction across ancestries
A cellular and spatial map of the choroid plexus across brain ventricles and ages
Early sample tagging and pooling enables simultaneous SARS-CoV-2 detection and variant sequencing
Single cell biology—a Keystone Symposia report
Disease-associated astrocytes in Alzheimer’s disease and aging
Single cell RNA sequencing of human microglia uncovers a subset associated with Alzheimer’s disease
SARS-CoV-2 detection with ApharSeq v3
Nuclei multiplexing with barcoded antibodies for single-nucleus genomics
Massively parallel single-nucleus RNA-seq with DroNc-seq
Div-Seq: Single-nucleus RNA-Seq reveals dynamics of rare adult newborn neurons
Nuclear receptors control pro-viral and antiviral metabolic responses to hepatitis C virus infection
Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex