Area of research
Structural Biology · Molecular Biology
Research interest
Research interests include Advanced Electron Microscopy Techniques and Applications, Electron and X-Ray Spectroscopy Techniques, RNA and protein synthesis mechanisms, and RNA modifications and cancer.
A new statistical metric for robust target detection in cryo-EM using 2D template matching
<i>In situ</i> high-resolution cryo-EM reconstructions from CEMOVIS
Decreased cytoplasmic crowding via inhibition of ribosome biogenesis can trigger Candida albicans filamentous growth
Structural basis for non-AUG translation regulation by 5MPs
CTFFIND5 provides improved insight into quality, tilt, and thickness of TEM samples
CTFFIND5 provides improved insight into quality, tilt and thickness of TEM samples
CTFFIND5 provides improved insight into quality, tilt and thickness of TEM samples
CTFFIND5 provides improved insight into quality, tilt, and thickness of TEM samples
From primordial clocks to circadian oscillators
Baited reconstruction with 2D template matching for high-resolution structure determination in vitro and in vivo without template bias
Baited reconstruction with 2D template matching for high-resolution structure determination in vitro and in vivo without template bias
Exploring the Limits of 2D Template Matching for Detecting Targets in Cellular Cryo-EM Images
Baited reconstruction with 2D template matching for high-resolution structure determination in vitro and in vivo without template bias
Baited reconstruction with 2D template matching for high-resolution structure determination in vitro and in vivo without template bias
In situ single particle classification reveals distinct 60S maturation intermediates in cells
Defocus Corrected Large Area Cryo-EM (DeCo-LACE) for label-free detection of molecules across entire cell sections
Locating macromolecular assemblies in cells by 2D template matching with cisTEM
Structure and assembly of calcium homeostasis modulator proteins
Structure of the Vesicular Stomatitis Virus L Protein in Complex with Its Phosphoprotein Cofactor
mRNA stem-loops can pause the ribosome by hindering A-site tRNA binding
Structure and assembly of calcium homeostasis modulator proteins.
Publisher Correction: Structure and assembly of calcium homeostasis modulator proteins
Cryo-EM fibril structures from systemic AA amyloidosis reveal the species complementarity of pathological amyloids
High-resolution cryo-EM structures of outbreak strain human norovirus shells reveal size variations
In situ structure determination at nanometer resolution using TYGRESS
In situ Structure of Rotavirus VP1 RNA-Dependent RNA Polymerase
Severing Enzymes Amplify Microtubule Arrays through Lattice GTP-Tubulin Incorporation
cisTEM, user-friendly software for single-particle image processing
Severing enzymes amplify microtubule arrays through lattice GTP-tubulin incorporation
Physical basis of amyloid fibril polymorphism