Area of research
Cellular and Molecular Neuroscience · Molecular Biology
Research interest
Research interests include Neuroscience and Neuropharmacology Research, Ion channel regulation and function, Clinical Nutrition and Gastroenterology, and Organ Transplantation Techniques and Outcomes.
Structural basis for channel gating and blockade in tri-heteromeric GluN1-2B-2D NMDA receptor
Mechanism of conductance control and neurosteroid binding in NMDA receptors
Molecular mechanism of ligand gating and opening of NMDA receptor
Structural insights into assembly and function of GluN1-2C, GluN1-2A-2C, and GluN1-2D NMDARs
Structure, Function, and Pharmacology of Glutamate Receptor Ion Channels
On the molecular nature of large-pore channels
The Cryo-EM structure of pannexin 1 reveals unique motifs for ion selection and inhibition
Structure and assembly of calcium homeostasis modulator proteins
Structure and assembly of calcium homeostasis modulator proteins.
Hodgkin–Huxley–Katz Prize Lecture: Genetic and pharmacological control of glutamate receptor channel through a highly conserved gating motif
Publisher Correction: Structure and assembly of calcium homeostasis modulator proteins
Structural elements of a pH-sensitive inhibitor binding site in NMDA receptors
Structure, function, and allosteric modulation of NMDA receptors
Structural Mechanism of Functional Modulation by Gene Splicing in NMDA Receptors
Structural Mechanism for Modulation of Synaptic Neuroligin-Neurexin Signaling by MDGA Proteins
Divergent roles of a peripheral transmembrane segment in AMPA and NMDA receptors
Activation of NMDA receptors and the mechanism of inhibition by ifenprodil
Structural Insights into Competitive Antagonism in NMDA Receptors
Structural Determinants and Mechanism of Action of a GluN2C-selective NMDA Receptor Positive Allosteric Modulator
Structural Determinants of Agonist Efficacy at the Glutamate Binding Site of N-Methyl-d-Aspartate Receptors
Mapping the Binding of GluN2B-Selective N-Methyl-d-aspartate Receptor Negative Allosteric Modulators