Area of research
Molecular Biology · Cellular and Molecular Neuroscience
Research interest
Research interests include Neuroscience and Neuropharmacology Research, Ion channel regulation and function, Receptor Mechanisms and Signaling, and Polyamine Metabolism and Applications.
Negative allosteric modulation of GluN1/GluN3 NMDA receptors
NMDA receptor channel gating control by the pre-M1 helix
Distinct GluN1 and GluN2 Structural Determinants for Subunit-Selective Positive Allosteric Modulation of <i>N</i>-Methyl-<scp>d</scp>-aspartate Receptors
One Among Millions: The Chemical Space of Nucleic Acid-Like Molecules
A structurally derived model of subunit‐dependent NMDA receptor function
An NMDAR positive and negative allosteric modulator series share a binding site and are interconverted by methyl groups
Functional Evaluation of a De Novo GRIN2A Mutation Identified in a Patient with Profound Global Developmental Delay and Refractory Epilepsy
Mechanistic Insight into NMDA Receptor Dysregulation by Rare Variants in the GluN2A and GluN2B Agonist Binding Domains
Structural Determinants and Mechanism of Action of a GluN2C-selective NMDA Receptor Positive Allosteric Modulator
Mapping the Binding of GluN2B-Selective N-Methyl-d-aspartate Receptor Negative Allosteric Modulators