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Daniela Mercatelli

University of Ferrara · IT
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Area of research
Neurology · Cellular and Molecular Neuroscience
Research interest
Research interests include LRRK2, Dopaminergic, Nociceptin receptor, NOP, Dopamine, and Substantia nigra.
h-index
citations
438
works
23
NIH funding
primary concept
email

Recent publications

Enhancement of D1 dopaminergic responses in aged LRRK2 G2019S knock-in mice
Neurobiology of Disease 2025cited by 2position: firstdoi
Viral mediated α-synuclein overexpression results in greater transgene levels and α-synuclein overload in mice bearing kinase dead mutation of LRRK2
Scientific Reports 2025cited by 1position: middledoi
Development of a new toolbox for mouse PET–CT brain image analysis fully based on CT images and validation in a PD mouse model
Scientific Reports 2022cited by 11position: middledoi
Dopamine Transporter, PhosphoSerine129 α-Synuclein and α-Synuclein Levels in Aged LRRK2 G2019S Knock-In and Knock-Out Mice
Biomedicines 2022cited by 11position: middledoi
Constitutive silencing of LRRK2 kinase activity leads to early glucocerebrosidase deregulation and late impairment of autophagy in vivo
Neurobiology of Disease 2021cited by 30position: middledoi
In vivo susceptibility to energy failure parkinsonism and LRRK2 kinase activity
Neurobiology of Disease 2021cited by 20position: middledoi
Early Dysfunction of Substantia Nigra Dopamine Neurons in the ParkinQ311X Mouse
Biomedicines 2021cited by 6position: middledoi
Regulator of G‐Protein Signalling 4 (RGS4) negatively modulates nociceptin/orphanin FQ opioid receptor signalling: Implication for <scp>l</scp>‐Dopa‐induced dyskinesia
British Journal of Pharmacology 2021cited by 4position: middledoi
RGS4 negatively modulates Nociceptin/Orphanin FQ opioid receptor signaling: implication for L-Dopa induced dyskinesia
2021cited by 0position: middledoi
Constitutive Silencing of LRRK2 Kinase Activity Leads to Early Glucocerebrosidase Deregulation and Late Impairment of Autophagy in vivo
Research Square 2021cited by 0position: middledoi
Pharmacological antagonism of kainate receptor rescues dysfunction and loss of dopamine neurons in a mouse model of human parkin-induced toxicity
Cell Death and Disease 2020cited by 25position: middledoi
Discovery and Structure–Activity Relationships of Nociceptin Receptor Partial Agonists That Afford Symptom Ablation in Parkinson’s Disease Models
Journal of Medicinal Chemistry 2020cited by 9position: middledoi
Pharmacological Antagonism of Kainate Receptor Rescues Dysfunction and Loss of Dopamine Neurons in a Mouse Model of Human Parkin-induced Toxicity
2020cited by 6position: middledoi
Gene Co-expression Analysis Identifies Histone Deacetylase 5 and 9 Expression in Midbrain Dopamine Neurons and as Regulators of Neurite Growth via Bone Morphogenetic Protein Signaling
Frontiers in Cell and Developmental Biology 2019cited by 19position: middledoi
Leucine‐rich repeat kinase 2 (<scp>LRRK</scp>2) inhibitors differentially modulate glutamate release and Serine935 <scp>LRRK</scp>2 phosphorylation in striatal and cerebrocortical synaptosomes
Pharmacology Research & Perspectives 2019cited by 18position: firstdoi
Managing Parkinson's disease: moving ON with NOP
British Journal of Pharmacology 2019cited by 16position: firstdoi
Leucine-rich repeat kinase 2 controls protein kinase A activation state through phosphodiesterase 4
Journal of Neuroinflammation 2018cited by 50position: middledoi
Influence of neuropathic pain on nicotinic acetylcholine receptor plasticity and behavioral responses to nicotine in rats
Pain 2018cited by 17position: middledoi
NOP Receptor Ligands and Parkinson’s Disease
Handbook of experimental pharmacology 2018cited by 12position: firstdoi
Age-dependent dopamine transporter dysfunction and Serine129 phospho-α-synuclein overload in G2019S LRRK2 mice
Acta Neuropathologica Communications 2017cited by 97position: middledoi
Anti‐Parkinsonian and anti‐dyskinetic profiles of two novel potent and selective nociceptin/orphanin FQ receptor agonists
British Journal of Pharmacology 2017cited by 22position: middledoi
Parkinson’s disease: no NOP, new hope
Oncotarget 2016cited by 6position: middledoi
Eltoprazine prevents levodopa‐induced dyskinesias by reducing striatal glutamate and direct pathway activity
Movement Disorders 2015cited by 56position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Michele Morari · University of Ferrara22 papers (2015–2025)Federica Albanese · New York University9 papers (2020–2025)Alberto Brugnoli · University of Ferrara8 papers (2015–2025)Salvatore Novello · University of Ferrara8 papers (2017–2022)Derya R. Shimshek · Novartis (Switzerland)6 papers (2017–2025)Clarissa Anna Pisanò · Karolinska Institutet6 papers (2017–2021)Nurulain T. Zaveri · Wake Forest University5 papers (2017–2021)Ludovico Arcuri · University of Ferrara4 papers (2015–2017)Gerard W. O’Keeffe · Cardiff University3 papers (2019–2021)Riccardo Brambilla · Cardiff University3 papers (2017–2021)Jenny Sassone · University of Ferrara3 papers (2020–2021)Laura Croci · Vita-Salute San Raffaele University3 papers (2020–2021) · 3 papers (2020–2021)Stefania Fasano · Cardiff University3 papers (2017–2021)Ilaria Morella · Cardiff University3 papers (2017–2021)G. Giacomo Consalez · Vita-Salute San Raffaele University3 papers (2020–2021) · 3 papers (2020–2021) · 3 papers (2020–2021)Erwan Bézard · Centre National de la Recherche Scientifique3 papers (2019–2025)Chiara Domenicale · University of Ferrara3 papers (2021–2025)
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