Area of research
Neurology · Cellular and Molecular Neuroscience
Research interest
Research interests include LRRK2, Dopaminergic, Nociceptin receptor, NOP, Dopamine, and Substantia nigra.
Enhancement of D1 dopaminergic responses in aged LRRK2 G2019S knock-in mice
Viral mediated α-synuclein overexpression results in greater transgene levels and α-synuclein overload in mice bearing kinase dead mutation of LRRK2
Development of a new toolbox for mouse PET–CT brain image analysis fully based on CT images and validation in a PD mouse model
Dopamine Transporter, PhosphoSerine129 α-Synuclein and α-Synuclein Levels in Aged LRRK2 G2019S Knock-In and Knock-Out Mice
Constitutive silencing of LRRK2 kinase activity leads to early glucocerebrosidase deregulation and late impairment of autophagy in vivo
In vivo susceptibility to energy failure parkinsonism and LRRK2 kinase activity
Early Dysfunction of Substantia Nigra Dopamine Neurons in the ParkinQ311X Mouse
Regulator of G‐Protein Signalling 4 (RGS4) negatively modulates nociceptin/orphanin FQ opioid receptor signalling: Implication for <scp>l</scp>‐Dopa‐induced dyskinesia
RGS4 negatively modulates Nociceptin/Orphanin FQ opioid receptor signaling: implication for L-Dopa induced dyskinesia
Constitutive Silencing of LRRK2 Kinase Activity Leads to Early Glucocerebrosidase Deregulation and Late Impairment of Autophagy in vivo
Pharmacological antagonism of kainate receptor rescues dysfunction and loss of dopamine neurons in a mouse model of human parkin-induced toxicity
Discovery and Structure–Activity Relationships of Nociceptin Receptor Partial Agonists That Afford Symptom Ablation in Parkinson’s Disease Models
Pharmacological Antagonism of Kainate Receptor Rescues Dysfunction and Loss of Dopamine Neurons in a Mouse Model of Human Parkin-induced Toxicity
Gene Co-expression Analysis Identifies Histone Deacetylase 5 and 9 Expression in Midbrain Dopamine Neurons and as Regulators of Neurite Growth via Bone Morphogenetic Protein Signaling
Leucine‐rich repeat kinase 2 (<scp>LRRK</scp>2) inhibitors differentially modulate glutamate release and Serine935 <scp>LRRK</scp>2 phosphorylation in striatal and cerebrocortical synaptosomes
Managing Parkinson's disease: moving ON with NOP
Leucine-rich repeat kinase 2 controls protein kinase A activation state through phosphodiesterase 4
Influence of neuropathic pain on nicotinic acetylcholine receptor plasticity and behavioral responses to nicotine in rats
NOP Receptor Ligands and Parkinson’s Disease
Age-dependent dopamine transporter dysfunction and Serine129 phospho-α-synuclein overload in G2019S LRRK2 mice
Anti‐Parkinsonian and anti‐dyskinetic profiles of two novel potent and selective nociceptin/orphanin FQ receptor agonists
Parkinson’s disease: no NOP, new hope
Eltoprazine prevents levodopa‐induced dyskinesias by reducing striatal glutamate and direct pathway activity