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David R. Mack

University of Ottawa · CA
🔎 Find collaborators in Genetics · Epidemiology →
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Area of research
Genetics · Epidemiology
Research interest
Research interests include Inflammatory Bowel Disease, Microscopic Colitis, Gut microbiota and health, and Adolescent and Pediatric Healthcare.
h-index
62
citations
18,477
works
457
NIH funding
primary concept
Medicine
email

Recent publications

Automated Eosinophil Quantification Using Deep Learning to Predict Therapy Escalation in Pediatric Ulcerative Colitis.
2026cited by 0position: contributordoi
Metabolomics reveal distinct molecular pathways associated with future risk of Crohn’s Disease
Gut Microbes 2025cited by 3position: middledoi
Metabolomics reveal distinct molecular pathways associated with future risk of Crohn's Disease.
2025cited by 2position: contributordoi
Perspectives of Adolescents and Young Adults With Inflammatory Bowel Disease on a Biopsychosocial Transition Intervention: Qualitative Interview Study.
2025cited by 2position: contributordoi
Perspectives of Adolescents and Young Adults With Inflammatory Bowel Disease on a Biopsychosocial Transition Intervention: Qualitative Interview Study
JMIR Pediatrics and Parenting 2025cited by 2position: middledoi
The colonic mucosal virome in inflammatory bowel disease reveals Crassvirales depletion and disease-specific virome features.
2025cited by 1position: contributordoi
Reply to R Kellermayer.
2025cited by 0position: contributordoi
Linking microbial genes to plasma and stool metabolites uncovers host-microbial interactions underlying ulcerative colitis disease course
Cell Host & Microbe 2024cited by 70position: middledoi
Machine Learning–Based Prediction of Pediatric Ulcerative Colitis Treatment Response Using Diagnostic Histopathology
Gastroenterology 2024cited by 22position: middledoi
Healthy First-Degree Relatives From Multiplex Families vs Simplex Families Have Higher Subclinical Intestinal Inflammation, a Distinct Fecal Microbial Signature, and Harbor a Higher Risk of Developing Crohn’s Disease
Gastroenterology 2024cited by 20position: middledoi
Adalimumab vs Infliximab in Luminal Pediatric Crohn's Disease: Comparable Outcomes in a Prospective Multicenter Cohort Study.
2024cited by 9position: contributordoi
The intestinal microbiome, but not clinical aspects of inflammatory bowel disease, is impacted by lactose malabsorption compared to lactose digestion in children.
2024cited by 1position: contributordoi
Butyrate's role in human health and the current progress towards its clinical application to treat gastrointestinal disease.
2023cited by 239position: contributordoi
Immune response and barrier dysfunction-related proteomic signatures in preclinical phase of Crohn’s disease highlight earliest events of pathogenesis
Gut 2023cited by 71position: middledoi
Mucosal transcriptomics highlight lncRNAs implicated in ulcerative colitis, Crohn's disease, and celiac disease.
2023cited by 12position: contributordoi
The Benefit of Early and Frequent Antitumor Necrosis Factor-Alpha Trough Level Determination in Very Early-Onset Inflammatory Bowel Disease.
2023cited by 1position: contributordoi
Altered Gut Microbiome Composition and Function Are Associated With Gut Barrier Dysfunction in Healthy Relatives of Patients With Crohn’s Disease
Gastroenterology 2022cited by 188position: middledoi
Mediterranean-Like Dietary Pattern Associations With Gut Microbiome Composition and Subclinical Gastrointestinal Inflammation
Gastroenterology 2022cited by 110position: middledoi
Thromboprophylaxis Use in Paediatric Inflammatory Bowel Disease: An International RAND Appropriateness Panel
Journal of Crohn s and Colitis 2022cited by 12position: middledoi
Development and Validation of the TUMMY-UC: A Patient-Reported Outcome for Pediatric Ulcerative Colitis
Gastroenterology 2022cited by 11position: middledoi
Thromboprophylaxis Use in Paediatric Inflammatory Bowel Disease: An International RAND Appropriateness Panel.
2022cited by 8position: contributordoi
Clinical and Host Biological Factors Predict Colectomy Risk in Children Newly Diagnosed With Ulcerative Colitis
Inflammatory Bowel Diseases 2021cited by 23position: middledoi
Clinical and biological predictors of response to standardised paediatric colitis therapy (PROTECT): a multicentre inception cohort study
The Lancet 2019cited by 163position: middledoi
Analysis of Genetic Association of Intestinal Permeability in Healthy First-degree Relatives of Patients with Crohn’s Disease
Inflammatory Bowel Diseases 2019cited by 26position: middledoi
The pediatric inflammatory bowel disease INTERMED: A new clinical tool to assess psychosocial needs
Journal of Psychosomatic Research 2019cited by 20position: lastdoi
Compositional and Temporal Changes in the Gut Microbiome of Pediatric Ulcerative Colitis Patients Are Linked to Disease Course
Cell Host & Microbe 2018cited by 302position: middledoi
The Impact of Inflammatory Bowel Disease in Canada 2018: Children and Adolescents with IBD
Journal of the Canadian Association of Gastroenterology 2018cited by 149position: middledoi
The Effect of Early-Life Environmental Exposures on Disease Phenotype and Clinical Course of Crohn's Disease in Children
The American Journal of Gastroenterology 2018cited by 47position: middledoi
Prediction of complicated disease course for children newly diagnosed with Crohn's disease: a multicentre inception cohort study
The Lancet 2017cited by 639position: middledoi
Trends in Epidemiology of Pediatric Inflammatory Bowel Disease in Canada: Distributed Network Analysis of Multiple Population-Based Provincial Health Administrative Databases
The American Journal of Gastroenterology 2017cited by 310position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Anne M. Griffiths · SickKids Foundation14 papers (2014–2025) · 10 papers (2022–2026)Jeffrey S. Hyams · S.P.E.C.I.E.S.7 papers (2014–2024)Thomas D. Walters · SickKids Foundation7 papers (2014–2025)Dan Turner · Oxford Nanopore Technologies (United Kingdom)6 papers (2015–2025)Eric I. Benchimol · University of Toronto5 papers (2017–2025)Anthony Otley · Dalhousie University5 papers (2016–2024)Lee A. Denson · S.P.E.C.I.E.S.4 papers (2014–2024)Kevan Jacobson · Immune Deficiency Foundation4 papers (2017–2025)Subra Kugathasan · Emory University4 papers (2014–2024)Alain Bitton · McGill University Health Centre3 papers (2017–2025)Joel R. Rosh · North Shore Diabetes and Endocrine Associates3 papers (2014–2021)David C. Wilson · Centre for Inflammation Research3 papers (2017–2022)James Markowitz · Hospital for Sick Children3 papers (2014–2021)Wallace Crandall · The Ohio State University3 papers (2014–2017)Çharles N. Bernstein · University of Manitoba3 papers (2017–2025)Robert N. Baldassano · Pennsylvania Hospital3 papers (2014–2021)Gilaad G. Kaplan · Mount Sinai Hospital2 papers (2017–2018)Matthew Carroll · University of Alberta2 papers (2017–2018)Susan S. Baker · Hospital for Sick Children2 papers (2014–2017)
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