Area of research
Genetics · Epidemiology
Research interest
Research focused on Crohn's disease and Disease, with related work in Microbiome, Pathogenesis, Expression quantitative trait loci. Notable publications include 'The Treatment-Naive Microbiome in New-Onset Crohn’s Disease', 'Prediction of complicated disease course for children newly diagnosed with Crohn's disease: a multicentre inception cohort study', and 'Pediatric Crohn disease patients exhibit specific ileal transcriptome and microbiome signature'.
Efficacy and safety of mirikizumab in patients with moderately-to-severely active Crohn's disease: a phase 3, multicentre, randomised, double-blind, placebo-controlled and active-controlled, treat-through study
Paediatric Inflammatory Bowel Disease: A Multi-Stakeholder Perspective to Improve Development of Drugs for Children and Adolescents
Blood-Derived DNA Methylation Signatures of Crohn's Disease and Severity of Intestinal Inflammation
Serum Protein Biomarkers of Fibrosis Aid in Risk Stratification of Future Stricturing Complications in Pediatric Crohn's Disease
Clinical and Genomic Correlates of Neutrophil Reactive Oxygen Species Production in Pediatric Patients With Crohn’s Disease
Long ncRNA Landscape in the Ileum of Treatment-Naive Early-Onset Crohn Disease
The Effect of Early-Life Environmental Exposures on Disease Phenotype and Clinical Course of Crohn's Disease in Children
Age-of-diagnosis dependent ileal immune intensification and reduced alpha-defensin in older versus younger pediatric Crohn Disease patients despite already established dysbiosis
Genetic variants and pathways implicated in a pediatric inflammatory bowel disease cohort
Genetic and Transcriptomic Variation Linked to Neutrophil Granulocyte–Macrophage Colony-Stimulating Factor Signaling in Pediatric Crohn’s Disease
Prediction of complicated disease course for children newly diagnosed with Crohn's disease: a multicentre inception cohort study
Transcriptional risk scores link GWAS to eQTLs and predict complications in Crohn's disease
Mucosal Expression of Type 2 and Type 17 Immune Response Genes Distinguishes Ulcerative Colitis From Colon-Only Crohn’s Disease in Treatment-Naive Pediatric Patients
Dissecting Allele Architecture of Early Onset IBD Using High-Density Genotyping
The Telehealth Enhancement of Adherence to Medication (TEAM) in pediatric IBD trial: Design and methodology
Abdominal X‐ray in Pediatric Acute Severe Colitis and Radiographic Predictors of Response to Intravenous Steroids
The Treatment-Naive Microbiome in New-Onset Crohn’s Disease
Pediatric Crohn disease patients exhibit specific ileal transcriptome and microbiome signature
Effectiveness of Anti-TNFα for Crohn Disease: Research in a Pediatric Learning Health System
Increased Effectiveness of Early Therapy With Anti-Tumor Necrosis Factor-α vs an Immunomodulator in Children With Crohn's Disease