Area of research
Genetics · Epidemiology
Research interest
Research focused on Ulcerative colitis and Crohn's disease, with related work in Disease, Mesalazine, Pathogenesis. Notable publications include 'Prediction of complicated disease course for children newly diagnosed with Crohn's disease: a multicentre inception cohort study', 'Pediatric Crohn disease patients exhibit specific ileal transcriptome and microbiome signature', and 'Ulcerative colitis mucosal transcriptomes reveal mitochondriopathy and personalized mechanisms underlying disease severity and treatment response'.
Machine Learning–Based Prediction of Pediatric Ulcerative Colitis Treatment Response Using Diagnostic Histopathology
Progression of Pediatric Crohn’s Disease Is Associated With Anti–Tumor Necrosis Factor Timing and Body Mass Index Z-Score Normalization
Utilization of Antitumor Necrosis Factor Biologics in Very Early Onset Inflammatory Bowel Disease
<i>Natural History of </i> Very Early Onset Inflammatory Bowel Disease <i>in North America: A Retrospective Cohort Study</i>
Mucosal Inflammatory and Wound Healing Gene Programmes Reveal Targets for Stricturing Behaviour in Paediatric Crohn’s Disease
Clinical and biological predictors of response to standardised paediatric colitis therapy (PROTECT): a multicentre inception cohort study
Blood-Derived DNA Methylation Signatures of Crohn's Disease and Severity of Intestinal Inflammation
Serum Protein Biomarkers of Fibrosis Aid in Risk Stratification of Future Stricturing Complications in Pediatric Crohn's Disease
Ulcerative colitis mucosal transcriptomes reveal mitochondriopathy and personalized mechanisms underlying disease severity and treatment response
Compositional and Temporal Changes in the Gut Microbiome of Pediatric Ulcerative Colitis Patients Are Linked to Disease Course
Clinical and Genomic Correlates of Neutrophil Reactive Oxygen Species Production in Pediatric Patients With Crohn’s Disease
Long ncRNA Landscape in the Ileum of Treatment-Naive Early-Onset Crohn Disease
Enhanced Contribution of HLA in Pediatric Onset Ulcerative Colitis
The Effect of Early-Life Environmental Exposures on Disease Phenotype and Clinical Course of Crohn's Disease in Children
Age-of-diagnosis dependent ileal immune intensification and reduced alpha-defensin in older versus younger pediatric Crohn Disease patients despite already established dysbiosis
Genetic variants and pathways implicated in a pediatric inflammatory bowel disease cohort
Genetic and Transcriptomic Variation Linked to Neutrophil Granulocyte–Macrophage Colony-Stimulating Factor Signaling in Pediatric Crohn’s Disease
Prediction of complicated disease course for children newly diagnosed with Crohn's disease: a multicentre inception cohort study
Transcriptional risk scores link GWAS to eQTLs and predict complications in Crohn's disease
Factors associated with early outcomes following standardised therapy in children with ulcerative colitis (PROTECT): a multicentre inception cohort study
Mucosal Expression of Type 2 and Type 17 Immune Response Genes Distinguishes Ulcerative Colitis From Colon-Only Crohn’s Disease in Treatment-Naive Pediatric Patients
Can You Teach a Teen New Tricks? Problem Solving Skills Training Improves Oral Medication Adherence in Pediatric Patients with Inflammatory Bowel Disease Participating in a Randomized Trial
Pediatric Crohn disease patients exhibit specific ileal transcriptome and microbiome signature