Area of research
Cell Biology · Molecular Biology
Research interest
Research interests include Microtubule and mitosis dynamics, Fungal and yeast genetics research, DNA Repair Mechanisms, and Genomic variations and chromosomal abnormalities.
A breakage–replication/fusion process explains complex rearrangements and segmental DNA amplification
ERα-associated translocations underlie oncogene amplifications in breast cancer
Heritable transcriptional defects from aberrations of nuclear architecture
A tubule-sheet continuum model for the mechanism of nuclear envelope assembly
Author Correction: Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing
Abstract 6105: Unravelling the mechanistic basis of chromoplexy, a mutational process driving early cancer genome evolution
Breakage of cytoplasmic chromosomes by pathological DNA base excision repair
Cancer Genomic Rearrangements and Copy Number Alterations from Errors in Cell Division
Chromothripsis as an on-target consequence of CRISPR–Cas9 genome editing
Whole chromosome loss and genomic instability in mouse embryos after CRISPR-Cas9 genome editing
Decoding complex patterns of oncogene amplification
Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing
Mechanisms generating cancer genome complexity from a single cell division error
The coordination of nuclear envelope assembly and chromosome segregation in metazoans
Factors promoting nuclear envelope assembly independent of the canonical ESCRT pathway
The Ubiquitin Ligase TRAIP: Double-Edged Sword at the Replisome
Publisher Correction: Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing
Mitotic CDK Promotes Replisome Disassembly, Fork Breakage, and Complex DNA Rearrangements
Nuclear envelope assembly defects link mitotic errors to chromothripsis
Cells Lacking the <i>RB1</i> Tumor Suppressor Gene Are Hyperdependent on Aurora B Kinase for Survival
Trisomy of a Down Syndrome Critical Region Globally Amplifies Transcription via HMGN1 Overexpression
Human nuclear RNAi-defective 2 (NRDE2) is an essential RNA splicing factor
A Tubulin Binding Switch Underlies Kip3/Kinesin-8 Depolymerase Activity
Cell Biology: When Your Own Chromosomes Act like Foreign DNA
Genome jail-break triggers lockdown
The EMT regulator ZEB2 is a novel dependency of human and murine acute myeloid leukemia
Chromothripsis from DNA damage in micronuclei
Polyploidy can drive rapid adaptation in yeast
Chromothripsis: A New Mechanism for Rapid Karyotype Evolution
Direct Microtubule-Binding by Myosin-10 Orients Centrosomes toward Retraction Fibers and Subcortical Actin Clouds