Area of research
Physiology · Molecular Biology
Research interest
Research interests include Biology, Cell biology, CRISPR, Genome editing, Induced pluripotent stem cell, and Cas9.
RNA methyltransferase NSun2 deficiency promotes neurodegeneration through epitranscriptomic regulation of tau phosphorylation
Genuine selective caspase-2 inhibition with new irreversible small peptidomimetics
Pluripotent stem cell-derived epithelium misidentified as brain microvascular endothelium requires ETS factors to acquire vascular fate
NSun2 deficiency promotes tau hyperphosphorylation and neurodegeneration through epitranscriptomic regulation of miR-125b
Autophagy Induction by Bexarotene Promotes Mitophagy in Presenilin 1 Familial Alzheimer’s Disease iPSC-Derived Neural Stem Cells
CRISPR/Cas9 editing of APP C-terminus attenuates β-cleavage and promotes α-cleavage
Mitophagy Failure in Fibroblasts and iPSC-Derived Neurons of Alzheimer’s Disease-Associated Presenilin 1 Mutation
Efficient introduction of specific homozygous and heterozygous mutations using CRISPR/Cas9