Area of research
Molecular Biology · Oncology
Research interest
Research interests include RNA and protein synthesis mechanisms, Cancer-related Molecular Pathways, Protein Structure and Dynamics, and Monoclonal and Polyclonal Antibodies Research.
YTHDF proteins and m6A-RNA clients undergo autophagic turnover during contact inhibition
K48- and K63-linked ubiquitin chain interactome reveals branch- and length-specific ubiquitin interactors
Cryo-EM structure of cell-free synthesized human histamine 2 receptor/Gs complex in nanodisc environment
Ubiquitination regulates ER-phagy and remodelling of endoplasmic reticulum
Cryo-EM structure of cell-free synthesized human histamine H <sub>2</sub> receptor coupled to heterotrimeric G <sub>s</sub> protein in lipid nanodisc environment
Disease‐linked TDP‐43 hyperphosphorylation suppresses TDP‐43 condensation and aggregation
Design, Synthesis, and Evaluation of WD-Repeat-Containing Protein 5 (WDR5) Degraders
The UBA domain of conjugating enzyme Ubc1/Ube2K facilitates assembly of K48/K63‐branched ubiquitin chains
Characterization of a natural variant of human NDP52 and its functional consequences on mitophagy
A dimerization-dependent mechanism regulates enzymatic activation and nuclear entry of PLK1
Design, Synthesis and Evaluation of WD-repeat containing protein 5 (WDR5) degraders
Ubiquitination in the ERAD Process
Regulation of Phosphoribosyl-Linked Serine Ubiquitination by Deubiquitinases DupA and DupB
Cell cycle arrest in mitosis promotes interferon-induced necroptosis
HUWE1 E3 ligase promotes PINK1/PARKIN-independent mitophagy by regulating AMBRA1 activation via IKKα
Oocyte DNA damage quality control requires consecutive interplay of CHK2 and CK1 to activate p63
Chain Assembly and Disassembly Processes Differently Affect the Conformational Space of Ubiquitin Chains
Phosphorylation of the mitochondrial autophagy receptor Nix enhances its interaction with LC3 proteins
Structural and functional analysis of the GABARAP interaction motif (GIM)
Analyzing native membrane protein assembly in nanodiscs by combined non-covalent mass spectrometry and synthetic biology
Structural and functional dissection of the DH and PH domains of oncogenic Bcr-Abl tyrosine kinase
Apoptosis inhibitor 5 is an endogenous inhibitor of caspase‐2
The CUE Domain of Cue1 Aligns Growing Ubiquitin Chains with Ubc7 for Rapid Elongation
From Nanodiscs to Isotropic Bicelles: A Procedure for Solution Nuclear Magnetic Resonance Studies of Detergent-Sensitive Integral Membrane Proteins
TECPR2 Cooperates with LC3C to Regulate COPII-Dependent ER Export
CUL3-KBTBD6/KBTBD7 Ubiquitin Ligase Cooperates with GABARAP Proteins to Spatially Restrict TIAM1-RAC1 Signaling
Structure and Biophysical Characterization of the S-Adenosylmethionine-dependent O-Methyltransferase PaMTH1, a Putative Enzyme Accumulating during Senescence of Podospora anserina
FAM96A is a novel pro-apoptotic tumor suppressor in gastrointestinal stromal tumors
Interactions between Autophagy Receptors and Ubiquitin-like Proteins Form the Molecular Basis for Selective Autophagy
Functional interplay between MDM2, p63/p73 and mutant p53