Area of research
Epidemiology · Molecular Biology
Research interest
Research interests include Autophagy in Disease and Therapy, Magnetic properties of thin films, Ubiquitin and proteasome pathways, and Endoplasmic Reticulum Stress and Disease.
Critical assessment of LC3/GABARAP ligands used for degrader development and ligandability of LC3/GABARAP binding pockets
Atg8 family proteins, LIR/AIM motifs and other interaction modes
Targeting LC3/GABARAP for degrader development and autophagy modulation
A Toolbox for the Generation of Chemical Probes for Baculovirus IAP Repeat Containing Proteins
Characterization of a natural variant of human NDP52 and its functional consequences on mitophagy
Atg8-Family Proteins—Structural Features and Molecular Interactions in Autophagy and Beyond
Ubiquitination in the ERAD Process
Regulation of Phosphoribosyl-Linked Serine Ubiquitination by Deubiquitinases DupA and DupB
HUWE1 E3 ligase promotes PINK1/PARKIN-independent mitophagy by regulating AMBRA1 activation via IKKα
Chain Assembly and Disassembly Processes Differently Affect the Conformational Space of Ubiquitin Chains
Structural Characterization of the Interaction of the Fibroblast Growth Factor Receptor with a Small Molecule Allosteric Inhibitor
Phosphorylation of the mitochondrial autophagy receptor Nix enhances its interaction with LC3 proteins
Structural and functional analysis of the GABARAP interaction motif (GIM)
Structural and Functional Analysis of a Novel Interaction Motif within UFM1-activating Enzyme 5 (UBA5) Required for Binding to Ubiquitin-like Proteins and Ufmylation
The CUE Domain of Cue1 Aligns Growing Ubiquitin Chains with Ubc7 for Rapid Elongation
TECPR2 Cooperates with LC3C to Regulate COPII-Dependent ER Export
CUL3-KBTBD6/KBTBD7 Ubiquitin Ligase Cooperates with GABARAP Proteins to Spatially Restrict TIAM1-RAC1 Signaling
Structure and Biophysical Characterization of the S-Adenosylmethionine-dependent O-Methyltransferase PaMTH1, a Putative Enzyme Accumulating during Senescence of Podospora anserina
Interactions between Autophagy Receptors and Ubiquitin-like Proteins Form the Molecular Basis for Selective Autophagy
Structural basis for phosphorylation-triggered autophagic clearance of <i>Salmonella</i>