Area of research
Molecular Biology · Cell Biology
Research interest
Research interests include Metabolism, Diabetes, and Cancer, Microtubule and mitosis dynamics, Receptor Mechanisms and Signaling, and Pancreatic function and diabetes.
Activation mechanism of the insulin receptor revealed by cryo-EM structure of the fully liganded receptor–ligand complex
Structural basis of the activation of type 1 insulin-like growth factor receptor
Mitotic regulators and the SHP2-MAPK pathway promote IR endocytosis and feedback regulation of insulin signaling
Spindle Checkpoint Regulators in Insulin Signaling
CPS1 maintains pyrimidine pools and DNA synthesis in KRAS/LKB1-mutant lung cancer cells
Mitotic Checkpoint Regulators Control Insulin Signaling and Metabolic Homeostasis