Area of research
Neurology · Physiology
Research interest
Research interests include Alzheimer's disease research and treatments, Parkinson's Disease Mechanisms and Treatments, Amyotrophic Lateral Sclerosis Research, and Autophagy in Disease and Therapy.
GRAMD1B is a regulator of lipid homeostasis, autophagic flux and phosphorylated tau
Processing of progranulin into granulins involves multiple lysosomal proteases and is affected in frontotemporal lobar degeneration
TSC1 loss increases risk for tauopathy by inducing tau acetylation and preventing tau clearance via chaperone-mediated autophagy
A Comprehensive Resource for Induced Pluripotent Stem Cells from Patients with Primary Tauopathies
Progranulin Stimulates the In Vitro Maturation of Pro-Cathepsin D at Acidic pH
The Progranulin Cleavage Products, Granulins, Exacerbate TDP-43 Toxicity and Increase TDP-43 Levels