Area of research
Neurology · Physiology
Research interest
Research interests include Parkinson's Disease Mechanisms and Treatments, Alzheimer's disease research and treatments, Amyotrophic Lateral Sclerosis Research, and HIV Research and Treatment.
Identification of the peptide Vulnusin, a wound signal that mediates mechanical-injury-induced nociception in Drosophila
Polyglutamine-mediated ribotoxicity disrupts proteostasis and stress responses in Huntington’s disease
A Legionella toxin exhibits tRNA mimicry and glycosyl transferase activity to target the translation machinery and trigger a ribotoxic stress response
A hierarchical assembly pathway directs the unique subunit arrangement of TRiC/CCT
Arabidopsis ACINUS is O-glycosylated and regulates transcription and alternative splicing of regulators of reproductive transitions
Processing of progranulin into granulins involves multiple lysosomal proteases and is affected in frontotemporal lobar degeneration
TSC1 loss increases risk for tauopathy by inducing tau acetylation and preventing tau clearance via chaperone-mediated autophagy
Cotranslational prolyl hydroxylation is essential for flavivirus biogenesis
Phosphorylation at distinct subcellular locations underlies specificity in mTORC2-mediated activation of SGK1 and Akt
Chemically induced vesiculation as a platform for studying TMEM16F activity
saRNA-guided Ago2 targets the RITA complex to promoters to stimulate transcription
The Arabidopsis B-box protein BZS1/BBX20 interacts with HY5 and mediates strigolactone regulation of photomorphogenesis
Activation of HIPK2 Promotes ER Stress-Mediated Neurodegeneration in Amyotrophic Lateral Sclerosis