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William G. Devine

Northeastern University · US
Area of research
Molecular Biology · Public Health, Environmental and Occupational Health
Research interest
Research interests include RNA and protein synthesis mechanisms, PI3K/AKT/mTOR signaling in cancer, Research on Leishmaniasis Studies, and Trypanosoma species research and implications.
h-index
15
citations
787
works
36
NIH funding
primary concept
email

Recent publications

Inhibition of translation initiation factor eIF4a inactivates heat shock factor 1 (HSF1) and exerts anti-leukemia activity in AML
Leukemia 2021cited by 42position: middledoi
Rocaglates Induce Gain-of-Function Alterations to eIF4A and eIF4F
Cell Reports 2020cited by 76position: middledoi
Amidino-Rocaglates: A Potent Class of eIF4A Inhibitors
Cell chemical biology 2019cited by 77position: middledoi
Targeting translation initiation by synthetic rocaglates for treating MYC-driven lymphomas
Leukemia 2019cited by 32position: middledoi
Inhibiting the oncogenic translation program is an effective therapeutic strategy in multiple myeloma
Science Translational Medicine 2017cited by 72position: middledoi
Antiparasitic Lead Discovery: Toward Optimization of a Chemotype with Activity Against Multiple Protozoan Parasites
ACS Medicinal Chemistry Letters 2017cited by 27position: firstdoi
Protozoan Parasite Growth Inhibitors Discovered by Cross-Screening Yield Potent Scaffolds for Lead Discovery
Journal of Medicinal Chemistry 2015cited by 73position: firstdoi
Antitrypanosomal Lead Discovery: Identification of a Ligand-Efficient Inhibitor of Trypanosoma cruzi CYP51 and Parasite Growth
Journal of Medicinal Chemistry 2013cited by 63position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

John A. Porco · Boston University5 papers (2017–2021)Lauren E. Brown · Boston University4 papers (2017–2020)Jessey Erath · New York University3 papers (2013–2017)Michael P. Pollastri · Northeastern University3 papers (2013–2017)Ana Rodrı́guez · New York University3 papers (2013–2017) · 2 papers (2015–2017)Luke Whitesell · University of Toronto2 papers (2017–2021)Patricia Lee · Griffith University2 papers (2015–2017)Emanuele Amata · Northeastern University2 papers (2013–2015)Jennifer Chu · McGill University2 papers (2019–2020)Regina Cencic · McGill University Health Centre2 papers (2019–2020)Wenhan Zhang · Amgen (United States)2 papers (2019–2020)Jerry Pelletier · McGill University2 papers (2019–2020)Kojo Mensa‐Wilmot · University of Georgia2 papers (2015–2017) · 2 papers (2019–2020) · 2 papers (2015–2017)Sándor Vajda · Boston University1 papers (2019–2019) · 1 papers (2021–2021)Salomon Manier · CANTHER - Hétérogénéité, Plasticité et Résistance aux Thérapies des Cancers1 papers (2017–2017)Jiantao Shi · Amgen (United States)1 papers (2017–2017)