Rachael Bartlett

Development of a targeted BioPROTAC degrader selective for misfolded SOD1

A polytherapy approach demonstrates therapeutic efficacy for the treatment of SOD1 associated amyotrophic lateral sclerosis

Associations of psychiatric disease and ageing with FKBP5 expression converge on superficial layer neurons of the neocortex

P2X7 receptor activation mediates superoxide dismutase 1 (SOD1) release from murine NSC-34 motor neurons

Pharmacological and genetic characterisation of the canine P2X4 receptor

P2X7 antagonism using Brilliant Blue G reduces body weight loss and prolongs survival in female SOD1 ^G93A amyotrophic lateral sclerosis mice

P2X7 receptor antagonism in amyotrophic lateral sclerosis

Probenecid directly impairs activation of the canine P2X7 receptor

The P2X7 Receptor Channel: Recent Developments and the Use of P2X7 Antagonists in Models of Disease

R270C polymorphism leads to loss of function of the canine P2X7 receptor

P2X7 Receptor Activation Induces Reactive Oxygen Species Formation and Cell Death in Murine EOC13 Microglia