Area of research
Nutrition and Dietetics · Molecular Biology
Research interest
Research interests include Chemistry, Biochemistry, GPX4, Glutathione, Selenocysteine, and Biology.
Unraveling the parahormetic mechanism underlying the health-protecting effects of grapeseed procyanidins
A white paper on Phospholipid Hydroperoxide Glutathione Peroxidase (GPx4) forty years later
Aerobic pyruvate metabolism sensitizes cells to ferroptosis primed by GSH depletion
PKCα Inhibition as a Strategy to Sensitize Neuroblastoma Stem Cells to Etoposide by Stimulating Ferroptosis
Homeostatic control of redox status and health
Grape Seeds Proanthocyanidins: Advanced Technological Preparation and Analytical Characterization
Lipid peroxidation and ferroptosis: The role of GSH and GPx4
A dual attack on the peroxide bond. The common principle of peroxidatic cysteine or selenocysteine residues
Insight into the mechanism of ferroptosis inhibition by ferrostatin-1
Inactivation of the glutathione peroxidase GPx4 by the ferroptosis‐inducing molecule RSL3 requires the adaptor protein 14‐3‐3ε
Phytosome complex of curcumin as complementary therapy of advanced pancreatic cancer improves safety and efficacy of gemcitabine: Results of a prospective phase II trial
Rust never sleeps: The continuing story of the Iron Bolt
Selenium Utilization by GPX4 Is Required to Prevent Hydroperoxide-Induced Ferroptosis
GPx4, Lipid Peroxidation, and Cell Death: Discoveries, Rediscoveries, and Open Issues
Glutathione peroxidase 4-catalyzed reduction of lipid hydroperoxides in membranes: The polar head of membrane phospholipids binds the enzyme and addresses the fatty acid hydroperoxide group toward the redox center
The Oxygen Paradox, the French Paradox, and age-related diseases
Redox homeostasis: The Golden Mean of healthy living
Effects of moderate beer consumption on health and disease: A consensus document
Selenoprotein Gene Nomenclature
Protein cysteine oxidation in redox signaling: Caveats on sulfenic acid detection and quantification
Selenocysteine oxidation in glutathione peroxidase catalysis: an MS-supported quantum mechanics study
Expression of a Catalytically Inactive Mutant Form of Glutathione Peroxidase 4 (Gpx4) Confers a Dominant-negative Effect in Male Fertility
Understanding mammalian glutathione peroxidase 7 in the light of its homologs
Glutathione peroxidase 8 is transcriptionally regulated by HIFα and modulates growth factor signaling in HeLa cells
An overview of mechanisms of redox signaling
Corrigendum to ‘‘How Do Nutritional Antioxidants Really Work: Nucleophilic Tone and Para-Hormesis Versus Free Radical Scavenging in vivo’’ [Free Radic. Biol. and Med. 66 (2014) 24–35]
How do nutritional antioxidants really work: Nucleophilic tone and para-hormesis versus free radical scavenging in vivo
Protein disulfide isomerase and glutathione are alternative substrates in the one Cys catalytic cycle of glutathione peroxidase 7
Cigarette smoke extract stimulates epithelial–mesenchymal transition through Src activation