Area of research
Nutrition and Dietetics · Molecular Biology
Research interest
Research interests include Chemistry, GPX4, Glutathione, Selenocysteine, Lipid peroxidation, and Phospholipid-hydroperoxide glutathione peroxidase.
Mitochondrial fission links ECM mechanotransduction to metabolic redox homeostasis and metastatic chemotherapy resistance
A white paper on Phospholipid Hydroperoxide Glutathione Peroxidase (GPx4) forty years later
Aerobic pyruvate metabolism sensitizes cells to ferroptosis primed by GSH depletion
PKCα Inhibition as a Strategy to Sensitize Neuroblastoma Stem Cells to Etoposide by Stimulating Ferroptosis
Insight into the mechanism of ferroptosis inhibition by ferrostatin-1
Inactivation of the glutathione peroxidase GPx4 by the ferroptosis‐inducing molecule RSL3 requires the adaptor protein 14‐3‐3ε
Selenium Utilization by GPX4 Is Required to Prevent Hydroperoxide-Induced Ferroptosis
Glutathione peroxidase 4-catalyzed reduction of lipid hydroperoxides in membranes: The polar head of membrane phospholipids binds the enzyme and addresses the fatty acid hydroperoxide group toward the redox center
Selenocysteine oxidation in glutathione peroxidase catalysis: an MS-supported quantum mechanics study
Expression of a Catalytically Inactive Mutant Form of Glutathione Peroxidase 4 (Gpx4) Confers a Dominant-negative Effect in Male Fertility
Understanding mammalian glutathione peroxidase 7 in the light of its homologs
Glutathione peroxidase 8 is transcriptionally regulated by HIFα and modulates growth factor signaling in HeLa cells
Protein disulfide isomerase and glutathione are alternative substrates in the one Cys catalytic cycle of glutathione peroxidase 7