Irina Ingold — Technical University of Munich

Area of research

Pulmonary and Respiratory Medicine · Nutrition and Dietetics

Research interest

Research focused on GPX4 and Phospholipid-hydroperoxide glutathione peroxidase, with related work in Selenocysteine, Cell biology, Programmed cell death. Notable publications include 'ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition', 'FSP1 is a glutathione-independent ferroptosis suppressor', and 'Selenium Utilization by GPX4 Is Required to Prevent Hydroperoxide-Induced Ferroptosis'.

Recent publications

A fin-loop-like structure in GPX4 underlies neuroprotection from ferroptosis

Cell 2025cited by 15position: middledoi

Dysfunction of the key ferroptosis-surveilling systems hypersensitizes mice to tubular necrosis during acute kidney injury

Nature Communications 2021cited by 246position: middledoi

FSP1 is a glutathione-independent ferroptosis suppressor

Nature 2019cited by 3,157position: middledoi

Nano-targeted induction of dual ferroptotic mechanisms eradicates high-risk neuroblastoma

Journal of Clinical Investigation 2018cited by 626position: middledoi

Selenium Utilization by GPX4 Is Required to Prevent Hydroperoxide-Induced Ferroptosis

Cell 2017cited by 1,592position: firstdoi

ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition

Nature Chemical Biology 2016cited by 3,961position: middledoi

Ultrasmall nanoparticles induce ferroptosis in nutrient-deprived cancer cells and suppress tumour growth

Nature Nanotechnology 2016cited by 631position: middledoi

Expression of a Catalytically Inactive Mutant Form of Glutathione Peroxidase 4 (Gpx4) Confers a Dominant-negative Effect in Male Fertility

Journal of Biological Chemistry 2015cited by 91position: firstdoi

Grants

No grants ingested yet.

Frequent collaborators

Marcus Conrad · Max Planck Institute of Biophysics5 papers (2015–2018)José Pedro Friedmann Angeli · Ludwig-Maximilians-Universität München4 papers (2015–2018)Sebastian Doll · Helmholtz Zentrum München3 papers (2015–2017)Wolfgang Wurst · German Center for Neurodegenerative Diseases3 papers (2015–2017)Michaela Aichler · Technical University of Munich3 papers (2015–2017)Axel Walch · University of Alaska Anchorage3 papers (2015–2017)Feng Qu · Ministry of Education2 papers (2016–2018)— · 2 papers (2015–2017)Fulvio Ursini · University of Padua2 papers (2015–2017)Valerian E. Kagan · University of Pittsburgh2 papers (2016–2018)Yulia Y. Tyurina · University of Pittsburgh2 papers (2016–2018)Antonella Roveri · University of Padua2 papers (2015–2017)Hülya Bayır · Columbia University2 papers (2016–2018)Feng Chen · Shenzhen University1 papers (2016–2016)Sung Eun Kim · Beth Israel Deaconess Medical Center1 papers (2016–2016)Li Zhang · Nanjing University of Chinese Medicine1 papers (2016–2016)Xiaoxiao Peng · Shanxi Medical University1 papers (2017–2017)Johannes Beckers · Georgetown University1 papers (2016–2016)Daniel Lamp · Technical University of Munich1 papers (2017–2017)Guy Van Camp · University of Antwerp1 papers (2018–2018)

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