Area of research
Genetics · Cellular and Molecular Neuroscience
Research interest
Research interests include Genetic Associations and Epidemiology, Genomic variations and chromosomal abnormalities, Genetic Neurodegenerative Diseases, and Genetics and Neurodevelopmental Disorders.
Genomics yields biological and phenotypic insights into bipolar disorder
Machine learning in Alzheimer’s disease genetics
Schizophrenia-associated somatic copy-number variants from 12,834 cases reveal recurrent NRXN1 and ABCB11 disruptions
New insights into the genetic etiology of Alzheimer’s disease and related dementias
Interaction Testing and Polygenic Risk Scoring to Estimate the Association of Common Genetic Variants With Treatment Resistance in Schizophrenia
Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology
Finding genetically-supported drug targets for Parkinson’s disease using Mendelian randomization of the druggable genome
A Comparison of Ten Polygenic Score Methods for Psychiatric Disorders Applied Across Multiple Cohorts
Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders
Schizophrenia, autism spectrum disorders and developmental disorders share specific disruptive coding mutations
Genetic contributors to risk of schizophrenia in the presence of a 22q11.2 deletion
New insights on the genetic etiology of Alzheimer’s and related dementia
Dystonia genes functionally converge in specific neurons and share neurobiology with psychiatric disorders
Regulatory sites for splicing in human basal ganglia are enriched for disease-relevant information
Genome-wide association study identifies 30 loci associated with bipolar disorder
Comparative genetic architectures of schizophrenia in East Asian and European populations
The Genetics of the Mood Disorder Spectrum: Genome-wide Association Analyses of More Than 185,000 Cases and 439,000 Controls
MSH3 modifies somatic instability and disease severity in Huntington’s and myotonic dystrophy type 1
Association of Genetic Liability to Psychotic Experiences With Neuropsychotic Disorders and Traits
Mitochondria function associated genes contribute to Parkinson’s Disease risk and later age at onset
The Relationship Between Polygenic Risk Scores and Cognition in Schizophrenia
Moving beyond neurons: the role of cell type-specific gene regulation in Parkinson’s disease heritability
Novel Insight Into the Etiology of Autism Spectrum Disorder Gained by Integrating Expression Data With Genome-wide Association Statistics
A transcriptome-wide association study implicates specific pre- and post-synaptic abnormalities in schizophrenia
A polygenic resilience score moderates the genetic risk for schizophrenia
Bipolar multiplex families have an increased burden of common risk variants for psychiatric disorders
Genetic Risk Underlying Psychiatric and Cognitive Symptoms in Huntington’s Disease
Low-frequency variation in TP53 has large effects on head circumference and intracranial volume
Gene-based analysis in HRC imputed genome wide association data identifies three novel genes for Alzheimer’s disease
Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection