Area of research
Molecular Biology · Pulmonary and Respiratory Medicine
Research interest
Research interests include Heme Oxygenase-1 and Carbon Monoxide, Autophagy in Disease and Therapy, Chronic Obstructive Pulmonary Disease (COPD) Research, and Neonatal Health and Biochemistry.
High-fat diet obesity exacerbates acute lung injury-induced dysregulation of fatty acid oxidation in alveolar epithelial type 2 cells.
Alveolar epithelial cells mitigate neutrophilic inflammation in lung injury through regulating mitochondrial fatty acid oxidation
Chitinase 3–like-1 Inhibits Innate Antitumor and Tissue Remodeling Immune Responses by Regulating CD47-SIRPα– and CD24-Siglec10–Mediated Phagocytosis
Mitochondria in health, disease, and aging
Mitochondria in health, disease, and aging.
Alveolar type II epithelial cell FASN maintains lipid homeostasis in experimental COPD
AMPK Activation: Respiratory Panacea?
Autophagy in major human diseases
Reversal of emphysema by restoration of pulmonary endothelial cells
Reversal of emphysema by restoration of pulmonary endothelial cells.
Association of plasma mitochondrial DNA with COPD severity and progression in the SPIROMICS cohort
Cigarette smoke-initiated autoimmunity facilitates sensitisation to elastin-induced COPD-like pathologies in mice
Association of urine mitochondrial DNA with clinical measures of COPD in the SPIROMICS cohort
Cell-free DNA in human ex vivo lung perfusate as a potential biomarker to predict the risk of primary graft dysfunction in lung transplantation
The NASA Twins Study: A multidimensional analysis of a year-long human spaceflight
Necroptosis: a crucial pathogenic mediator of human disease
Mitophagy-dependent macrophage reprogramming protects against kidney fibrosis
Mitofusins regulate lipid metabolism to mediate the development of lung fibrosis
Association of Elevated Plasma Interleukin-18 Level With Increased Mortality in a Clinical Trial of Statin Treatment for Acute Respiratory Distress Syndrome*
GLUT1-dependent glycolysis regulates exacerbation of fibrosis via AIM2 inflammasome activation
Diurnal Rhythms Spatially and Temporally Organize Autophagy
Circulating cell death biomarker TRAIL is associated with increased organ dysfunction in sepsis
DROSHA-Dependent AIM2 Inflammasome Activation Contributes to Lung Inflammation during Idiopathic Pulmonary Fibrosis
A community approach to mortality prediction in sepsis via gene expression analysis
RIPK3 promotes sepsis-induced acute kidney injury via mitochondrial dysfunction
Mitochondrial Dysfunction as a Pathogenic Mediator of Chronic Obstructive Pulmonary Disease and Idiopathic Pulmonary Fibrosis
Human Lung DNA Methylation Quantitative Trait Loci Colocalize with Chronic Obstructive Pulmonary Disease Genome-Wide Association Loci
Rapidly Improving ARDS in Therapeutic Randomized Controlled Trials
A phase I trial of low-dose inhaled carbon monoxide in sepsis-induced ARDS
RIPK3 promotes kidney fibrosis via AKT-dependent ATP citrate lyase