Area of research
Molecular Biology · Epidemiology
Research interest
Research interests include Heme Oxygenase-1 and Carbon Monoxide, Autophagy in Disease and Therapy, Neonatal Health and Biochemistry, and Hemoglobin structure and function.
Mitochondria in health, disease, and aging
Pathogenic Mechanisms Underlying Idiopathic Pulmonary Fibrosis
Heme Oxgenase-1, a Cardinal Modulator of Regulated Cell Death and Inflammation
CD148 Deficiency in Fibroblasts Promotes the Development of Pulmonary Fibrosis
Therapeutic Potential of Heme Oxygenase-1 and Carbon Monoxide in Acute Organ Injury, Critical Illness, and Inflammatory Disorders
Necroptosis: a crucial pathogenic mediator of human disease
Heme oxygenase-1/carbon monoxide as modulators of autophagy and inflammation
RIPK3 promotes sepsis-induced acute kidney injury via mitochondrial dysfunction
Mitochondrial Dysfunction as a Pathogenic Mediator of Chronic Obstructive Pulmonary Disease and Idiopathic Pulmonary Fibrosis
Autophagy: A Lysosome-Dependent Process with Implications in Cellular Redox Homeostasis and Human Disease
RIPK3 promotes kidney fibrosis via AKT-dependent ATP citrate lyase
Carbon monoxide-induced TFEB nuclear translocation enhances mitophagy/mitochondrial biogenesis in hepatocytes and ameliorates inflammatory liver injury
RIPK3 mediates pathogenesis of experimental ventilator-induced lung injury
NLRP3 Inflammasome Deficiency Protects Against Microbial Sepsis Via Increased Lipoxin B4 Synthesis
Carbon monoxide in lung cell physiology and disease
Carbon monoxide protects against hepatic steatosis in mice by inducing sestrin-2 via the PERK-eIF2α-ATF4 pathway
RETRACTED ARTICLE: NOX4-dependent fatty acid oxidation promotes NLRP3 inflammasome activation in macrophages
SESN2/sestrin2 suppresses sepsis by inducing mitophagy and inhibiting NLRP3 activation in macrophages
Age-Dependent Susceptibility to Pulmonary Fibrosis Is Associated with NLRP3 Inflammasome Activation
Autophagy: Friend or Foe in Lung Disease?
RETRACTED: mTORC1-Induced HK1-Dependent Glycolysis Regulates NLRP3 Inflammasome Activation
Targeting heme oxygenase-1 and carbon monoxide for therapeutic modulation of inflammation
Oxidative stress and autophagy: Crucial modulators of kidney injury
UCP2-induced fatty acid synthase promotes NLRP3 inflammasome activation during sepsis
IRG1 induced by heme oxygenase-1/carbon monoxide inhibits LPS-mediated sepsis and pro-inflammatory cytokine production
Endoplasmic Reticulum Stress–Induced IRE1α Activation Mediates Cross-Talk of GSK-3β and XBP-1 To Regulate Inflammatory Cytokine Production
Regulation and Function of the Nucleotide Binding Domain Leucine-Rich Repeat-Containing Receptor, Pyrin Domain-Containing-3 Inflammasome in Lung Disease
Autophagy in lung disease pathogenesis and therapeutics
Carbon monoxide protects against hepatic ischemia/reperfusion injury by modulating the miR-34a/SIRT1 pathway
Mitophagy-dependent necroptosis contributes to the pathogenesis of COPD