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James M. McDonnell

King's College London · GB
Area of research
Radiology, Nuclear Medicine and Imaging · Immunology
Research interest
Research interests include Monoclonal and Polyclonal Antibodies Research, Mast cells and histamine, T-cell and B-cell Immunology, and Glycosylation and Glycoproteins Research.
h-index
35
citations
7,871
works
148
NIH funding
primary concept
email

Recent publications

IgE, IgE Receptors and Anti-IgE Biologics: Protein Structures and Mechanisms of Action
Annual Review of Immunology 2023cited by 41position: firstdoi
Vitamin D (1,25(OH)2D3) induces α-1-antitrypsin synthesis by CD4+ T cells, which is required for 1,25(OH)2D3-driven IL-10
The Journal of Steroid Biochemistry and Molecular Biology 2019cited by 32position: middledoi
A Mass‐Spectrometry‐Based Modelling Workflow for Accurate Prediction of IgG Antibody Conformations in the Gas Phase
Angewandte Chemie International Edition 2018cited by 48position: middledoi
Deep sequencing of HIV-1 reverse transcripts reveals the multifaceted antiviral functions of APOBEC3G
Nature Microbiology 2017cited by 110position: middledoi
Allosteric mechanism of action of the therapeutic anti-IgE antibody omalizumab
Journal of Biological Chemistry 2017cited by 86position: middledoi
IgE binds asymmetrically to its B cell receptor CD23
Scientific Reports 2017cited by 37position: middledoi
Ontogeny of human IgE-expressing B cells and plasma cells
Allergy 2016cited by 61position: middledoi
Antibodies and superantibodies in patients with chronic rhinosinusitis with nasal polyps
Journal of Allergy and Clinical Immunology 2016cited by 47position: middledoi
Inhibition of allergen‐dependent IgE activity by antibodies of the same specificity but different class
Allergy 2015cited by 63position: middledoi
Human immunoglobulin E flexes between acutely bent and extended conformations
Nature Structural & Molecular Biology 2014cited by 62position: middledoi
The CD46-Jagged1 interaction is critical for human TH1 immunity
Nature Immunology 2012cited by 199position: middledoi
Crystal structure of IgE bound to its B-cell receptor CD23 reveals a mechanism of reciprocal allosteric inhibition with high affinity receptor FcεRI
Proceedings of the National Academy of Sciences 2012cited by 91position: middledoi
Allergen specificity of IgG4-expressing B cells in patients with grass pollen allergy undergoing immunotherapy
Journal of Allergy and Clinical Immunology 2012cited by 82position: middledoi
Soluble CD23 Controls IgE Synthesis and Homeostasis in Human B Cells
The Journal of Immunology 2012cited by 75position: middledoi
Crystal structure of the human IgG4 CH3 dimer reveals the role of Arg409 in the mechanism of Fab-arm exchange
Molecular Immunology 2012cited by 42position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Brian J. Sutton · King's College London10 papers (2012–2023)Hannah J. Gould · King's College London9 papers (2012–2023)Andrew J. Beavil · Tobii (United Kingdom)7 papers (2012–2017)Louisa K. James · Queen Mary University of London4 papers (2012–2017)B. Dhaliwal · Almirall (Spain)3 papers (2012–2023)Anna M. Davies · King's College London3 papers (2012–2017)Marie O. Y. Pang · King's College London3 papers (2012–2017)H. J. M. Bowen · National Maritime Museum3 papers (2012–2016) · 3 papers (2012–2017)Claudia Kemper · National Institutes of Health2 papers (2012–2019)Tihomir Dodev · NeRRe Therapeutics (United Kingdom)2 papers (2012–2015)Stephen R. Durham · Lawrence Livermore National Laboratory2 papers (2012–2015)David J. Fear · King's College London2 papers (2012–2016) · 2 papers (2016–2016) · 2 papers (2014–2017) · 2 papers (2014–2017)Mohamed H. Shamji · Lung Institute2 papers (2012–2015) · 2 papers (2012–2014) · 2 papers (2012–2014)Michael W. Kao · King's College London2 papers (2012–2014)