Area of research
Molecular Biology · Oncology
Research interest
Research interests include DNA Repair Mechanisms, PARP inhibition in cancer therapy, Advanced Fluorescence Microscopy Techniques, and Advanced biosensing and bioanalysis techniques.
ORC1 binds to cis-transcribed RNAs for efficient activation of replication origins
Replication gaps are a key determinant of PARP inhibitor synthetic lethality with BRCA deficiency
Single-molecule imaging reveals replication fork coupled formation of G-quadruplex structures hinders local replication stress signaling
A basal-level activity of ATR links replication fork surveillance and stress response
Cancer-associated mutations in the iron-sulfur domain of FANCJ affect G-quadruplex metabolism
Super-resolution visualization of distinct stalled and broken replication fork structures
BRCA2 controls DNA:RNA hybrid level at DSBs by mediating RNase H2 recruitment
Spatiotemporal dynamics of homologous recombination repair at single collapsed replication forks