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Melissa Walker

Massachusetts General Hospital · US
Area of research
Genetics · Molecular Biology
Research interest
Research interests include Genomics and Rare Diseases, Metabolism and Genetic Disorders, Mitochondrial Function and Pathology, and Genetics and Neurodevelopmental Disorders.
h-index
29
citations
4,822
works
158
NIH funding
primary concept
email

Recent publications

T cell activation contributes to purifying selection against the MELAS‐associated m.3243A>G pathogenic variant in blood
Journal of Inherited Metabolic Disease 2024cited by 6position: firstdoi
<i>SPTSSA</i> variants alter sphingolipid synthesis and cause a complex hereditary spastic paraplegia
Brain 2023cited by 34position: middledoi
Circulating markers of NADH-reductive stress correlate with mitochondrial disease severity
Journal of Clinical Investigation 2021cited by 191position: middledoi
On the dynamic and even reversible nature of Leigh syndrome: Lessons from human imaging and mouse models
Current Opinion in Neurobiology 2021cited by 20position: firstdoi
MitoCarta3.0: an updated mitochondrial proteome now with sub-organelle localization and pathway annotations
Nucleic Acids Research 2020cited by 1,930position: middledoi
De Novo Variants in the ATPase Module of MORC2 Cause a Neurodevelopmental Disorder with Growth Retardation and Variable Craniofacial Dysmorphism
The American Journal of Human Genetics 2020cited by 110position: middledoi
Purifying Selection against Pathogenic Mitochondrial DNA in Human T Cells
New England Journal of Medicine 2020cited by 97position: firstdoi
Clinical sites of the Undiagnosed Diseases Network: unique contributions to genomic medicine and science
Genetics in Medicine 2020cited by 42position: middledoi
De novo mutations in TOMM70, a receptor of the mitochondrial import translocase, cause neurological impairment
Human Molecular Genetics 2020cited by 40position: middledoi
Phenotypic spectrum and transcriptomic profile associated with germline variants in TRAF7
Genetics in Medicine 2020cited by 33position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Vamsi K. Mootha · Harvard University4 papers (2020–2024)Amel Karaa · Massachusetts General Hospital2 papers (2020–2024)Devin Oglesbee · Mayo Clinic1 papers (2021–2021)Debdeep Dutta · Texas Children's Hospital1 papers (2020–2020)Catherine J. Wu · Dana-Farber/Harvard Cancer Center1 papers (2024–2024)Ashok Khatri · Harvard University1 papers (2021–2021)Darryl C. De Vivo · Columbia University Irving Medical Center1 papers (2021–2021)Caleb A. Lareau · Gladstone Institutes1 papers (2020–2020)Kenneth J. Livak · Broad Institute1 papers (2024–2024)Clary B. Clish · Broad Institute1 papers (2021–2021)Shinya Yamamoto · Kyoto University1 papers (2020–2020)Xiangling Mao · Cornell University1 papers (2021–2021)Ronald G. Haller · Southwestern Medical Center1 papers (2021–2021)Kristin Engelstad · Columbia University1 papers (2021–2021)Guy Helman · Hospital for Sick Children1 papers (2020–2020) · 1 papers (2021–2021)David A. Sweetser · Massachusetts General Hospital1 papers (2020–2020)Amanda L. Allred · Lake Forest College1 papers (2021–2021)Joel B. Krier · The University of Sydney1 papers (2020–2020)Leif S. Ludwig · Max Delbrück Center1 papers (2020–2020)