Area of research
Oncology · Genetics
Research interest
Research interests include Cancer Immunotherapy and Biomarkers, Chronic Lymphocytic Leukemia Research, Immunotherapy and Immune Responses, and CAR-T cell therapy research.
A neoantigen vaccine generates antitumour immunity in renal cell carcinoma
HIF regulates multiple translated endogenous retroviruses: Implications for cancer immunotherapy
Presence of Tertiary Lymphoid Structures and Exhausted Tissue-Resident T Cells Determines Clinical Response to PD-1 Blockade in Renal Cell Carcinoma
First-in-human evaluation of memory-like NK cells with an IL-15 super-agonist and CTLA-4 blockade in advanced head and neck cancer
Genomic mediators of acquired resistance to immunotherapy in metastatic melanoma
Coordinated immune networks in leukemia bone marrow microenvironments distinguish response to cellular therapy
Superoxide-mediated phosphorylation and stabilization of Mcl-1 by AKT underlie venetoclax resistance in hematologic malignancies
A phase I/II trial of WT1-specific TCR gene therapy for patients with acute myeloid leukemia and active disease post-allogeneic hematopoietic cell transplantation: skewing towards NK-like phenotype impairs T cell function and persistence
Mechanisms of immune escape and extramedullary tropism in leukemia cutis
Early persistence of recipient stem-cells and T-cell dysregulation are associated with relapse after transplant in AML/MDS
Fine tuning of CpG spatial distribution with DNA origami for improved cancer vaccination
Immune responses in checkpoint myocarditis across heart, blood and tumour
Non-pathogenic E. coli displaying decoy-resistant IL18 mutein boosts anti-tumor and CAR NK cell responses
Integrative genotyping of cancer and immune phenotypes by long-read sequencing
Oncogene-induced TIM-3 ligand expression dictates susceptibility to anti–TIM-3 therapy in mice
Systematic identification of minor histocompatibility antigens predicts outcomes of allogeneic hematopoietic cell transplantation
A multidimensional analysis reveals distinct immune phenotypes and the composition of immune aggregates in pediatric acute myeloid leukemia
CKLF instigates a “cold” microenvironment to promote MYCN-mediated tumor aggressiveness
Tracking Rare Single Donor and Recipient Immune and Leukemia Cells after Allogeneic Hematopoietic Cell Transplantation Using Mitochondrial DNA Mutations
T cell activation contributes to purifying selection against the MELAS‐associated m.3243A>G pathogenic variant in blood
Diagnosing recipient- vs. donor-derived posttransplant myelodysplastic neoplasm via targeted single-cell mutational profiling
Design of Cytotoxic T Cell Epitopes by Machine Learning of Human Degrons
Dynamics and specificities of T cells in cancer immunotherapy
Dictionary of immune responses to cytokines at single-cell resolution
Slide-tags enables single-nucleus barcoding for multimodal spatial genomics
Preexisting tumor-resident T cells with cytotoxic potential associate with response to neoadjuvant anti–PD-1 in head and neck cancer
Evolutionary history of transformation from chronic lymphocytic leukemia to Richter syndrome
Mechanisms of response and resistance to combined decitabine and ipilimumab for advanced myeloid disease
Hyperphosphorylation of BCL-2 family proteins underlies functional resistance to venetoclax in lymphoid malignancies
ALK peptide vaccination restores the immunogenicity of ALK-rearranged non-small cell lung cancer