Area of research
Cancer Research · Genetics
Research interest
Research interests include Cancer Genomics and Diagnostics, Chronic Lymphocytic Leukemia Research, Brain Metastases and Treatment, and Lung Cancer Treatments and Mutations.
CD38 in Advanced Prostate Cancers
Addendum: The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity
Clonal evolution in patients with chronic lymphocytic leukaemia developing resistance to BTK inhibition
Integrative Clinical Genomics of Advanced Prostate Cancer
Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas
Genomic Characterization of Brain Metastases Reveals Branched Evolution and Potential Therapeutic Targets
Mutations driving CLL and their evolution in progression and relapse
Comprehensive analysis of cancer-associated somatic mutations in class I HLA genes
Whole-genome sequencing reveals activation-induced cytidine deaminase signatures during indolent chronic lymphocytic leukaemia evolution
Deficiency of UBE2T, the E2 Ubiquitin Ligase Necessary for FANCD2 and FANCI Ubiquitination, Causes FA-T Subtype of Fanconi Anemia
Quantitative Clonal Dynamics Define Mechanisms of CLL Evolution in Response to Combination Chemotherapy
Comprehensive molecular characterization of gastric adenocarcinoma
Comprehensive molecular characterization of urothelial bladder carcinoma
Widespread Genetic Heterogeneity in Multiple Myeloma: Implications for Targeted Therapy
Whole-exome sequencing of circulating tumor cells provides a window into metastatic prostate cancer
Complementary genomic approaches highlight the PI3K/mTOR pathway as a common vulnerability in osteosarcoma
Locally Disordered Methylation Forms the Basis of Intratumor Methylome Variation in Chronic Lymphocytic Leukemia
Systematic identification of personal tumor-specific neoantigens in chronic lymphocytic leukemia
Genetic and Clonal Dissection of Murine Small Cell Lung Carcinoma Progression by Genome Sequencing
Subclonal Driver Mutations Predict Shorter Progression Free Survival in Chronic Lymphocytic Leukemia Following First-Line Chemo(immuno)Therapy: Results from the CLL8 Trial
Mutational heterogeneity in cancer and the search for new cancer-associated genes
The Somatic Genomic Landscape of Glioblastoma
Pan-cancer patterns of somatic copy number alteration
Evolution and Impact of Subclonal Mutations in Chronic Lymphocytic Leukemia
The genetic landscape of high-risk neuroblastoma
Exome and whole-genome sequencing of esophageal adenocarcinoma identifies recurrent driver events and mutational complexity
Sensitive detection of somatic point mutations in impure and heterogeneous cancer samples
Mutations causing medullary cystic kidney disease type 1 lie in a large VNTR in MUC1 missed by massively parallel sequencing
Clonal Evolution In Patients With Chronic Lymphocytic Leukemia (CLL) Developing Resistance To BTK Inhibition
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity