Area of research
Immunology · Molecular Biology
Research interest
Research interests include Immunotherapy and Immune Responses, Immune Cell Function and Interaction, Cancer Immunotherapy and Biomarkers, and vaccines and immunoinformatics approaches.
A neoantigen vaccine generates antitumour immunity in renal cell carcinoma
HIF regulates multiple translated endogenous retroviruses: Implications for cancer immunotherapy
Fine tuning of CpG spatial distribution with DNA origami for improved cancer vaccination
Systematic identification of minor histocompatibility antigens predicts outcomes of allogeneic hematopoietic cell transplantation
CKLF instigates a “cold” microenvironment to promote MYCN-mediated tumor aggressiveness
Design of Cytotoxic T Cell Epitopes by Machine Learning of Human Degrons
Dictionary of immune responses to cytokines at single-cell resolution
ALK peptide vaccination restores the immunogenicity of ALK-rearranged non-small cell lung cancer
Lynch syndrome cancer vaccines: A roadmap for the development of precision immunoprevention strategies
YAP1 and WWTR1 expression inversely correlates with neuroendocrine markers in Merkel cell carcinoma
Landscape of helper and regulatory antitumour CD4+ T cells in melanoma
Improved T-cell Immunity Following Neoadjuvant Chemotherapy in Ovarian Cancer
Reversal of viral and epigenetic HLA class I repression in Merkel cell carcinoma
Rare variants and HLA haplotypes associated in patients with neuromyelitis optica spectrum disorders
HLA-I immunopeptidome profiling of human cells infected with high-containment enveloped viruses
Phenotype, specificity and avidity of antitumour CD8+ T cells in melanoma
Progressive immune dysfunction with advancing disease stage in renal cell carcinoma
Personal neoantigen vaccines induce persistent memory T cell responses and epitope spreading in patients with melanoma
Unannotated proteins expand the MHC-I-restricted immunopeptidome in cancer
Profiling SARS-CoV-2 HLA-I peptidome reveals T cell epitopes from out-of-frame ORFs
Mapping the evolution of T cell states during response and resistance to adoptive cellular therapy
Optimized Liquid and Gas Phase Fractionation Increases HLA-Peptidome Coverage for Primary Cell and Tissue Samples
TANTIGEN 2.0: a knowledge base of tumor T cell antigens and epitopes
Applying high-dimensional single-cell technologies to the analysis of cancer immunotherapy
Automated Flow Synthesis of Tumor Neoantigen Peptides for Personalized Immunotherapy
A large peptidome dataset improves HLA class I epitope prediction across most of the human population
Mitochondrial Reprogramming Underlies Resistance to BCL-2 Inhibition in Lymphoid Malignancies
Neoantigen vaccine generates intratumoral T cell responses in phase Ib glioblastoma trial
Cancer-Germline Antigen Expression Discriminates Clinical Outcome to CTLA-4 Blockade
Detecting neoepitope-specific intra-tumoral T cell responses in a glioblastoma patient treated with personal neoantigen vaccine