Area of research
Molecular Biology · Immunology
Research interest
Research interests include Immunotherapy and Immune Responses, vaccines and immunoinformatics approaches, Monoclonal and Polyclonal Antibodies Research, and Cervical Cancer and HPV Research.
Vaccine-induced T cell receptor T cell therapy targeting a glioblastoma stemness antigen
Upstream open reading frame translation enhances immunogenic peptide presentation in mitotically arrested cancer cells
Highly sensitive live-cell imaging-based cytotoxicity assay enables functional validation of rare epitope-specific CTLs
A versatile silica nanoparticle platform for induction of T cell responses – applied for therapeutic vaccination against HPV16 E6/E7-positive tumors in MHC-humanized mice
Enhanced mutanome analysis towards the induction of neoepitope-reactive T-cell responses for personalized immunotherapy of pancreatic cancer
Upstream open reading frame translation enhances immunogenic peptide presentation in mitotically arrested cancer cells
Integrative spatial and multi-omic profiling in bladder cancer links L1 retrotransposition to extrachromosomal DNA, genomic instability, and viral mimicry response
optiPRM: A Targeted Immunopeptidomics LC-MS Workflow With Ultra-High Sensitivity for the Detection of Mutation-Derived Tumor Neoepitopes From Limited Input Material
Meeting report: Considerations for trial design and endpoints in licensing therapeutic HPV16/18 vaccines to prevent cervical cancer
MediMer: a versatile do-it-yourself peptide-receptive MHC class I multimer platform for tumor neoantigen-specific T cell detection
Transcriptome-based identification of tumor-reactive and bystander CD8 <sup>+</sup> T cell receptor clonotypes in human pancreatic cancer
Definition and Characterization of SOX11-Derived T Cell Epitopes towards Immunotherapy of Glioma
Development of an Orthotopic HPV16-Dependent Base of Tongue Tumor Model in MHC-Humanized Mice
Characterization of DoTc2 4510—Identifying HPV16 Presence in a Cervical Carcinoma Cell Line Previously Considered to Be HPV-Negative
The Importance of Being Presented: Target Validation by Immunopeptidomics for Epitope-Specific Immunotherapies
Light contamination in stable isotope-labelled internal peptide standards is frequent and a potential source of false discovery and quantitation error in proteomics
Effects of hypoxia on antigen presentation and T cell-based immune recognition of HPV16-transformed cells
Bacterial peptides presented on tumour cells could be immunotherapy targets
Light contamination in stable isotope-labelled internal peptide standards is frequent and a potential source of false discovery and quantitation error in proteomics
The shared frameshift mutation landscape of microsatellite-unstable cancers suggests immunoediting during tumor evolution
Inducing Immunity Where It Matters: Orthotopic HPV Tumor Models and Therapeutic Vaccinations
Application of individual HLA-binding prediction thresholds increases the detection of target cell surface-presented HPV16 E6- and E7-derived epitopes as a basis for therapeutic HPV vaccine design
Abstract A33: High-throughput prediction of MHC Class I and Class II neoantigens with MHCnuggets
High-Throughput Prediction of MHC Class I and II Neoantigens with MHCnuggets
Performance Evaluation of MHC Class-I Binding Prediction Tools Based on an Experimentally Validated MHC–Peptide Binding Data Set
Enhanced Radiation Sensitivity of Human Papillomavirus-Driven Head and Neck Cancer: Focus on Immunological Aspects
The shared <i>neo</i> antigen landscape of MSI cancers reflects immunoediting during tumor evolution
Abstract 578: Investigation of the effect of hypoxia on presentation of HPV16-derived antigens - implications for therapeutic vaccine design
Abstract 571: The shared mutation and <i>neo</i>antigen landscape of MMR-deficient colorectal cancers suggests immunoediting during tumor evolution
MHCflurry: Open-Source Class I MHC Binding Affinity Prediction